SCHEMBL19129707

SCHEMBL19129707

c1ccc(N(c2ccccc2)c2ccc(-c3cccc(-n4c5ccccc5c5c6oc7ccccc7c6ccc54)c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
BRCA1 P38398 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PLA2G2A P14555 3/20 0.32
PLA2G4A P47712 3/20 0.32
LMNA P02545 1/20 0.30
PPARG P37231 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
NR2E3 Q9Y5X4 1/20 0.30
NCOR2 Q9Y618 1/20 0.30
PLA2G10 O15496 1/20 0.30
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19129639 0.96 ALOX5 (0.33) ALOX5ALDH1A1MEN1POLBTSHR
SCHEMBL15582965 0.95 ALOX5 (0.33) ALOX5ALDH1A1KDM4EPLA2G2APLA2G4A
SCHEMBL15838249 0.94 ALDH1A1 (0.33) ALOX5ALDH1A1MEN1POLBTSHR
SCHEMBL26430813 0.94 MEN1 (0.33) ALDH1A1MEN1POLBTSHRBRCA1
SCHEMBL26430776 0.93 MEN1 (0.32) ALDH1A1MEN1POLBTSHRBRCA1
SCHEMBL26430816 0.93 MEN1 (0.32) ALDH1A1MEN1POLBTSHRBRCA1
SCHEMBL16409961 0.93 ALOX5 (0.33) ALOX5ALDH1A1MEN1POLBTSHR
SCHEMBL17426305 0.93 L3MBTL1 (0.37) ALDH1A1MEN1POLBTSHRBRCA1
SCHEMBL17426287 0.92 PLA2G2A (0.34) ALDH1A1MEN1POLBTSHRBRCA1
SCHEMBL18646637 0.92 KDM4E (0.35) ALOX5ALDH1A1MEN1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11387417-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-07-12 US disclosed
US-20200058882-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2020-02-20 US disclosed
US-20170207396-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-20 US disclosed
US-20170207396-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387417-B2 Organic electroluminescent device L3MBTL4, SLC39A14, CTCF ALOX5 1295/4885ALDH1A1 1852/4885MEN1 3528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.