Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30906191 | 0.96 | L3MBTL1 (0.61) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL6388281 | 0.90 | L3MBTL1 (0.61) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL13301486 | 0.85 | SMN1; SMN2 (0.69) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL12387048 | 0.85 | SMN1; SMN2 (0.69) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL269491 | 0.83 | L3MBTL1 (0.63) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL29375099 | 0.83 | L3MBTL1 (0.63) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL29365981 | 0.83 | L3MBTL1 (0.63) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL14582494 | 0.82 | L3MBTL1 (0.65) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL30646241 | 0.81 | L3MBTL1 (0.66) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL6748976 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KMT2AL3MBTL1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10835572-B2 | Composition for external application | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| EP-3210613-A1 | COMPOSITION FOR EXTERNAL APPLICATION | Rohto Pharmaceutical Co., Ltd. (JP) | 2017-08-30 | — | — | EP | disclosed |
| US-20170209522-A1 | Composition for External Application | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10835572-B2 | Composition for external application | COL1A1, COL14A1, COL2A1 | ALDH1A1 3193/4885KMT2A 3685/4885L3MBTL1 3372/4885 |
| US-20170209522-A1 | Composition for External Application | COL1A1, COL14A1, COL2A1 | ALDH1A1 3193/4885KMT2A 3685/4885L3MBTL1 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.