Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12792798 | 0.89 | ALDH1A1 (0.64) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL13301481 | 0.85 | SMN1; SMN2 (0.63) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL30646241 | 0.85 | L3MBTL1 (0.66) | ALDH1A1CYP3A4CA2LMNAL3MBTL1 | |
| SCHEMBL14582494 | 0.84 | L3MBTL1 (0.65) | ALDH1A1CYP3A4LMNAL3MBTL1MEN1 | |
| SCHEMBL30906191 | 0.83 | L3MBTL1 (0.61) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL269491 | 0.83 | L3MBTL1 (0.63) | ALDH1A1CYP3A4LMNAL3MBTL1MEN1 | |
| SCHEMBL29365981 | 0.83 | L3MBTL1 (0.63) | ALDH1A1CYP3A4LMNAL3MBTL1MEN1 | |
| SCHEMBL29375099 | 0.83 | L3MBTL1 (0.63) | ALDH1A1CYP3A4LMNAL3MBTL1MEN1 | |
| SCHEMBL13301464 | 0.82 | L3MBTL1 (0.69) | ALDH1A1CYP3A4LMNAL3MBTL1MEN1 | |
| SCHEMBL13301485 | 0.82 | L3MBTL1 (0.69) | ALDH1A1CYP3A4LMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323413-B1 | Light screening composition comprising a 1,3,5-triazine derivative, a dibenzoylmethane derivative and an amino substituted 2-hydroxybenzophenone derivative | L'ORÉAL (FR) | 2016-12-21 | — | — | EP | claimed |
| US-6703002-B2 | Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds | Societe L′Oreal S.A. (FR) | 2004-03-09 | — | — | US | claimed |
| US-6699460-B2 | UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-02 | — | — | US | claimed |
| US-6699461-B2 | UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-02 | — | — | US | claimed |
| US-6635239-B2 | Topically applicable cosmetic/dermatological self-tanning composition with colorations that are more chromatic, are more stable over time, and have good homogeneity | SOCIETE L'OREAL S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | claimed |
| US-6627179-B2 | Benzotriazole substituted silicon compound or polymer, dibenzoylmethane derivative and an amino-substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | claimed |
| US-20030180230-A1 | UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds | SOCIETE L'OREAL S.A. (FR) | 2003-09-25 | — | — | US | claimed |
| US-20030161793-A1 | UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds | SOCIETE L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | claimed |
| US-20030161794-A1 | Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds | SOCIETE L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | claimed |
| US-20030157038-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS | SOCIETE L'OREAL S.A. (FR) | 2003-08-21 | — | — | US | claimed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | claimed |
| US-20030129152-A1 | STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS | SOCIETE L'OREAL S.A. (FR) | 2003-07-10 | — | — | US | claimed |
| US-20150174045-A1 | LIGHT PROTECTING COMPOSITION WITH REDUCED TOTAL AMOUNT OF UV FILTER CONTAINING A POLYSILOXANE-BASED UV FILTER | DSM IP ASSETS B.V. (NL) | 2015-06-25 | — | — | US | disclosed |
| US-20070189994-A1 | Light protecting composition with reduced total amount of uv filter containing a polysiloxane-based uv filter | DSM IP ASSETS B.V. (NL) | 2007-08-16 | — | — | US | disclosed |
| US-6703002-B2 | Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds | Societe L′Oreal S.A. (FR) | 2004-03-09 | — | — | US | disclosed |
| US-20030161793-A1 | UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds | SOCIETE L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | disclosed |
| US-20030157038-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS | SOCIETE L'OREAL S.A. (FR) | 2003-08-21 | — | — | US | disclosed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20030129152-A1 | STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS | SOCIETE L'OREAL S.A. (FR) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030180230-A1 | UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds | DHPS, WEE2, DDT | ALDH1A1 205/4885CYP3A4 317/4885CA2 3557/4885 |
| US-20030161793-A1 | UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds | HADHB, HADH, NOTUM | ALDH1A1 108/4885CYP3A4 259/4885CA2 4049/4885 |
| US-20030161794-A1 | Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds | HADH, HADHB, BCAS2 | ALDH1A1 48/4885CYP3A4 1478/4885CA2 2887/4885 |
| US-20150174045-A1 | LIGHT PROTECTING COMPOSITION WITH REDUCED TOTAL AMOUNT OF UV FILTER CONTAINING A POLYSILOXANE-BASED UV FILTER | ERCC4, ERCC2, ERCC1 | ALDH1A1 2214/4885CYP3A4 1887/4885CA2 4344/4885 |
| US-20070189994-A1 | Light protecting composition with reduced total amount of uv filter containing a polysiloxane-based uv filter | ERCC4, ERCC2, PSMC6 | ALDH1A1 2087/4885CYP3A4 1903/4885CA2 4572/4885 |
| US-20030129152-A1 | STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS | TYR, MITF, CYP51A1 | ALDH1A1 302/4885CYP3A4 1321/4885CA2 4363/4885 |
| US-20030157038-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS | PSAT1, TST, BPTF | ALDH1A1 693/4885CYP3A4 964/4885CA2 4194/4885 |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | HADHB, SDHA, ERCC4 | ALDH1A1 193/4885CYP3A4 700/4885CA2 4558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.