Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3312632 | 0.90 | SLC6A4 (0.50) | PTPN1SLC6A4PTP4A3FAAHCNR2 | |
| SCHEMBL1914007 | 0.84 | FAAH (0.40) | FAAHCNR2CNR1MEN1KMT2A | |
| SCHEMBL3311321 | 0.80 | SLC6A4 (0.50) | PTPN1SLC6A4PTP4A3FAAHCNR2 | |
| SCHEMBL7932567 | 0.77 | TRPV6 (0.43) | PTPN1SLC6A4PTP4A3FAAHCNR2 | |
| SCHEMBL13505425 | 0.76 | HDAC11 (0.52) | ALDH1A1HTTHDAC11 | |
| SCHEMBL28093684 | 0.74 | MAOA (0.46) | PTPN1FAAHCNR2CNR1MAOB | |
| SCHEMBL3311180 | 0.74 | TRPV6 (0.44) | PTPN1SLC6A4PTP4A3FAAHCNR2 | |
| SCHEMBL7795284 | 0.74 | RARA (0.53) | FAAHCNR2CNR1MEN1KMT2A | |
| Water SCHEMBL27619796 | 0.74 | TRPV6 (0.46) | FAAHCNR2CNR1MEN1KMT2A | |
| SCHEMBL13330395 | 0.74 | TRPV6 (0.57) | SLC6A4FAAHCNR2CNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096544-B2 | Therapeutic compounds | WAYNE STATE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130137699-A1 | THERAPEUTIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2013-05-30 | — | — | US | disclosed |
| EP-2516396-A1 | THERAPEUTIC COMPOUNDS | Wayne State University (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011079305-A1 | THERAPEUTIC COMPOUNDS | WAYNE STATE UNIVERSITY (US) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137699-A1 | THERAPEUTIC COMPOUNDS | BAX, MCL1, TMBIM6 | PTPN1 2368/4885SLC6A4 3609/4885PTP4A3 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.