Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25558997 | 0.84 | MEN1 (0.43) | FAAHCNR2HDAC11ALDH1A1HPGD | |
| SCHEMBL3313324 | 0.83 | FAAH (0.53) | FAAHCNR2HDAC11ALDH1A1HDAC2 | |
| SCHEMBL25558996 | 0.79 | FAAH (0.45) | FAAHCNR2HDAC11ALDH1A1HDAC2 | |
| SCHEMBL23802006 | 0.78 | RARA (0.45) | FAAHERN1HDAC11ALDH1A1HPGD | |
| SCHEMBL1074076 | 0.78 | PKM (0.57) | FAAHCNR2ALDH1A1HPGDRARA | |
| SCHEMBL3309247 | 0.78 | HDAC11 (0.43) | FAAHCNR2HDAC11ALDH1A1HDAC2 | |
| SCHEMBL178217 | 0.78 | RARA (0.51) | FAAHCNR2HDAC11ALDH1A1HDAC2 | |
| SCHEMBL29535143 | 0.78 | RARA (0.51) | FAAHCNR2HDAC11ALDH1A1HDAC2 | |
| SCHEMBL9121523 | 0.77 | RARA (0.46) | FAAHCNR2HDAC11ALDH1A1HPGD | |
| SCHEMBL819782 | 0.77 | RARA (0.50) | FAAHCNR2HDAC11ALDH1A1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096544-B2 | Therapeutic compounds | WAYNE STATE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130137699-A1 | THERAPEUTIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2013-05-30 | — | — | US | disclosed |
| CN-102892755-A | Therapeutic compounds | UNIV WAYNE STATE | 2013-01-23 | — | — | CN | disclosed |
| EP-2516396-A1 | THERAPEUTIC COMPOUNDS | Wayne State University (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011079305-A1 | THERAPEUTIC COMPOUNDS | WAYNE STATE UNIVERSITY (US) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137699-A1 | THERAPEUTIC COMPOUNDS | BAX, MCL1, TMBIM6 | FAAH 4542/4885CNR2 4217/4885ERN1 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.