Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143330 | 0.81 | TGM2 (0.43) | SMN1; SMN2TAS2R38HSD17B10NAPRTTP53 | |
| SCHEMBL2914537 | 0.78 | NAPRT (0.52) | SMN1; SMN2HSD17B10NAPRTTP53TSHR | |
| SCHEMBL18464422 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2TAS2R38HSD17B10NAPRTTP53 | |
| SCHEMBL11183534 | 0.71 | MTOR (0.47) | SMN1; SMN2HSD17B10NAPRTTP53TSHR | |
| SCHEMBL5157140 | 0.70 | TAS2R38 (0.52) | SMN1; SMN2TAS2R38HSD17B10NAPRTTP53 | |
| SCHEMBL18676955 | 0.70 | TAS2R38 (0.52) | SMN1; SMN2TAS2R38HSD17B10NAPRTTP53 | |
| SCHEMBL13513997 | 0.70 | NPC1 (0.53) | SMN1; SMN2HSD17B10NAPRTTP53TSHR | |
| SCHEMBL12113186 | 0.69 | MAPT (0.61) | SMN1; SMN2TAS2R38HSD17B10NAPRTTP53 | |
| SCHEMBL12440049 | 0.69 | MAPT (0.61) | SMN1; SMN2TAS2R38HSD17B10NAPRTTP53 | |
| SCHEMBL9253909 | 0.69 | MAPT (0.61) | SMN1; SMN2TAS2R38HSD17B10NAPRTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10717724-B2 | Compounds useful for treating cancer | ABIVAX (FR) | 2020-07-21 | — | — | US | disclosed |
| US-20180222888-A1 | COMPOUNDS USEFUL FOR TREATING CANCER | ABIVAX (FR) | 2018-08-09 | — | — | US | disclosed |
| US-20170207396-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222888-A1 | COMPOUNDS USEFUL FOR TREATING CANCER | PRMT7, PRMT6, RRM2 | SMN1; SMN2 1893/4885TAS2R38 1224/4885HSD17B10 2740/4885 |
| US-10717724-B2 | Compounds useful for treating cancer | PRMT7, PRMT6, RRM2 | SMN1; SMN2 1893/4885TAS2R38 1224/4885HSD17B10 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.