SCHEMBL191464

SCHEMBL191464

Cl[SiH](Cl)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.45
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.41
LOXL2 Q9Y4K0 2/20 0.41
IDO1 P14902 2/20 0.41
TP53 P04637 1/20 0.41
TRPA1 O75762 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
MAOB P27338 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
F2 P00734 1/20 0.39
PLG P00747 1/20 0.39
ELANE P08246 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39
CTRC Q99895 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1041357 0.82 CALM1 (0.45) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL1538756 0.78 CALM1 (0.41) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL3192456 0.78 TP53 (0.43) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL28209612 0.78 CALM1 (0.48) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL2685711 0.77 HRH3 (0.41) TSHRIDO1MAOBTAAR1
SCHEMBL27765573 0.76 SIGMAR1 (0.41) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL41196 0.75 CALM1 (0.50) CALM1TSHRALDH1A1LOXL2IDO1
SCHEMBL4845187 0.74 CA1 (0.39)
SCHEMBL7054862 0.74 IDO1 (0.48) ALDH1A1IDO1MAOBTDP1CYP2A6
SCHEMBL15302450 0.74 TP53 (0.46) CALM1TSHRALDH1A1LOXL2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617947-B2 Flame-retardant flexible coating composition, flame-retardant product having flame-retardant flexible coating layer and method for manufacturing the same AXEED INC. (KR) 2026-05-05 US claimed
CN-116284797-B Rubber material containing polyborosiloxane and preparation method thereof 成都魔极科技有限公司 2024-05-28 CN claimed
CN-116285372-B Polyborosiloxane modified plastic and preparation method thereof 成都魔极科技有限公司 2024-05-28 CN claimed
US-20240076508-A1 FLAME-RETARDANT FLEXIBLE COATING COMPOSITION, FLAME-RETARDANT PRODUCT HAVING FLAME-RETARDANT FLEXIBLE COATING LAYER AND METHOD FOR MANUFACTURING THE SAME AXEED INC. (KR) 2024-03-07 US claimed
US-20240076528-A1 ADDITIVE COMPOSITION FOR FLAME RETARDANCY OF ADHESIVE, FLAME-RETARDANT ACRYLIC ADHESIVE, FLAME-RETARDANT TAPE USING THE SAME, AND MANUFACTURING METHOD THEREOF AXEED INC. (KR) 2024-03-07 US claimed
CN-117463293-A Adsorbent for wastewater detection and preparation method and application thereof 江苏中烟工业有限责任公司 2024-01-30 CN claimed
CN-116355493-A Flame-retardant resin paving material for tunnel and preparation method thereof 江苏中路工程技术研究院有限公司 2023-06-30 CN claimed
CN-115216013-A Poly-linked borosilicate siloxane rubber material and preparation method thereof 四川大学 2022-10-21 CN claimed
CN-111320715-B Ultrahigh molecular weight polyolefin catalyst, and preparation method and application thereof 叶平山 2022-10-04 CN claimed
CN-109796545-B Preparation method of antistatic ultrahigh molecular weight polyethylene 中国石油天然气股份有限公司 2021-08-27 CN claimed
US-4985579-A Reacting with a Hydrogen Halide, Separation by Distillation DOW CORNING CORPORATION (US) 1991-01-15 US claimed
EP-0269948-A2 Process for preparing modified polycycloolefins THE B.F. GOODRICH COMPANY (US) 1988-06-08 EP claimed
EP-0130338-B1 RESIST STRUCTURE AND PROCESSES FOR MAKING AND PATTERNING IT International Business Machines Corporation (US) 1988-05-04 EP claimed
EP-0130338-A2 Resist structure and processes for making and patterning it International Business Machines Corporation (US) 1985-01-09 EP claimed
US-4464460-A Process for making an imaged oxygen-reactive ion etch barrier INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1984-08-07 US claimed
EP-0077794-A1 SOLUBLE POLYSILASTYRENE AND METHOD FOR PREPARATION WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1983-05-04 EP claimed
WO-1982003862-A1 SOLUBLE POLYSILASTYRENE AND METHOD FOR PREPARATION WISCONSIN ALUMNI RES FOUND (US) 1982-11-11 WO claimed
US-4324901-A Soluble polysilastyrene and method for preparation WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1982-04-13 US claimed
US-4260780-A Phenylmethylpolysilane polymers and process for their preparation THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1981-04-07 US claimed
US-4228092-A BY ALCOHOL ESTERIFICATION DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-10-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617947-B2 Flame-retardant flexible coating composition, flame-retardant product having flame-retardant flexible coating layer and method for manufacturing the same PFAS, ITGB3, ITGA1 CALM1 3095/4885TSHR 604/4885ALDH1A1 1496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.