SCHEMBL1914764

SCHEMBL1914764

CCCCCCCCCCCC(=O)N(CCNCCO)CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 6/20 0.43
KDM4C Q9H3R0 6/20 0.43
PHF8 Q9UPP1 4/20 0.43
KDM5C P41229 1/20 0.41
KDM5B Q9UGL1 1/20 0.41
GPR84 Q9NQS5 7/20 0.41
PPARG P37231 7/20 0.41
PPARD Q03181 7/20 0.41
PPARA Q07869 7/20 0.41
HDAC11 Q96DB2 5/20 0.41
TSHR P16473 4/20 0.41
PTPN1 P18031 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TLR2 O60603 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FABP4 P15090 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
MEN1 O00255 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9722887 0.99 KDM5A (0.43) KDM5AKDM4CPHF8KDM5CKDM5B
Hydrochloric Acid SCHEMBL9722886 0.97 KDM4C (0.42) KDM5AKDM4CPHF8KDM5CKDM5B
SCHEMBL27987934 0.91 EPHX2 (0.50) PPARGPPARDPPARAPTPN1ALDH1A1
SCHEMBL9633196 0.87 DNM1 (0.43) KDM5AKDM4CPHF8ALDH1A1TDP1
SCHEMBL9633650 0.87 LMNA (0.44) KDM5AKDM4CPHF8HDAC11ALDH1A1
SCHEMBL11528503 0.85 KDM5A (0.47) KDM5AKDM4CPHF8KDM5CKDM5B
SCHEMBL10608799 0.85 GPR84 (0.48) KDM5AKDM4CPHF8GPR84PPARG
SCHEMBL10607949 0.83 GPR84 (0.47) KDM5AKDM4CPHF8GPR84PPARG
SCHEMBL10607000 0.83 GPR84 (0.47) KDM5AKDM4CPHF8GPR84PPARG
SCHEMBL10611435 0.83 GPR84 (0.47) KDM5AKDM4CPHF8GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0674616-B1 ALPHA-AMINO-SUBSTITUTED ACETIC ACID SALTS OR ACIDS AND COSMETIC USES THEREOF RHODIA CHIMIE SA (FR) 1998-07-29 EP claimed
CN-108137813-B Cured silicone particles and cosmetic materials incorporating cured silicone particles therein 陶氏东丽株式会社 2020-12-29 CN disclosed
EP-2516510-A1 SURFACE-TREATMENT AGENT FOR POWDER FOR USE IN COSMETIC AND COSMETIC CONTAINING POWDER TREATED WITH THE SAME Dow Corning Toray Co., Ltd. (JP) 2012-10-31 EP disclosed
EP-2515841-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME Dow Corning Toray Co., Ltd. (JP) 2012-10-31 EP disclosed
WO-2011078407-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed