Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.40 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633650 | 0.91 | LMNA (0.44) | DNM1KDM5APHF8KDM4CNAAA | |
| SCHEMBL11502569 | 0.90 | KDM5A (0.47) | KDM5APHF8KDM4CALDH1A1MEN1 | |
| SCHEMBL14937709 | 0.88 | KDM5A (0.46) | KDM5APHF8KDM4CALDH1A1MEN1 | |
| SCHEMBL25412654 | 0.88 | PAOX (0.46) | DNM1KDM5APHF8KDM4CNAAA | |
| SCHEMBL14937708 | 0.87 | GPR84 (0.40) | DNM1KDM5APHF8KDM4C | |
| SCHEMBL1914764 | 0.87 | KDM5A (0.43) | KDM5APHF8KDM4CALDH1A1MEN1 | |
| SCHEMBL5806921 | 0.87 | KDM5A (0.47) | KDM5APHF8KDM4CALDH1A1MEN1 | |
| SCHEMBL1914762 | 0.87 | KDM5A (0.47) | KDM5APHF8KDM4CALDH1A1MEN1 | |
| SCHEMBL5807681 | 0.87 | KDM5A (0.47) | KDM5APHF8KDM4CALDH1A1MEN1 | |
| SCHEMBL284784 | 0.87 | CES2 (0.48) | CNR1ALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162315-A | Topical administration of diltiazem | THERAPEUTIC PATCH RESEARCH N.V. | 1992-11-10 | — | — | US | disclosed |