Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | PDE5A | O76074 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306283 | 0.81 | ALOX15 (0.64) | CA2LMNASMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL2095593 | 0.80 | CA2 (1.00) | CA2LMNASMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL10579506 | 0.80 | PTGS2 (0.52) | SMN1; SMN2ALDH1A1CYP3A4TSHRCYP2C19 | |
| SCHEMBL10626018 | 0.77 | PDE10A (0.53) | CA2LMNASMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL11819246 | 0.77 | PDE10A (0.56) | CA2LMNASMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL28164756 | 0.77 | CA2 (0.91) | CA2LMNASMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL29449205 | 0.77 | CA2 (0.91) | CA2LMNASMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL83495 | 0.76 | CA2 (0.80) | CA2LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28097055 | 0.76 | LTA4H (0.59) | LMNASMN1; SMN2ALDH1A1MAPK1PDE10A | |
| SCHEMBL11822901 | 0.74 | PDE10A (0.58) | CA2LMNASMN1; SMN2ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2034965-A2 | PROCESS FOR PREPARING A SOLID DOSAGE FORM | UNIVERSITEIT GENT (BE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008000453-A2 | PROCESS FOR PREPARING A SOLID DOSAGE FORM | UNIVERSITEIT GENT (BE) | 2008-01-03 | — | — | WO | disclosed |
| EP-0580753-A1 | PYRIMIDINE DERIVATIVES FOR ENHANCING ANTITUMOR ACTIVITY. | PFIZER (US) | 1994-02-02 | — | — | EP | disclosed |
| WO-1992018498-A1 | PYRIMIDINE DERIVATIVES FOR ENHANCING ANTITUMOR ACTIVITY | PFIZER INC. (US) | 1992-10-29 | — | — | WO | disclosed |