Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123696 | 0.83 | MAPT (0.39) | MEN1APAF1CASP3KMT2APAX8 | |
| SCHEMBL11392957 | 0.82 | MAPT (0.40) | MEN1APAF1CASP3KMT2APAX8 | |
| SCHEMBL1152075 | 0.76 | MAPT (0.37) | MEN1APAF1CASP3KMT2APAX8 | |
| SCHEMBL29763992 | 0.67 | MAPT (0.56) | MEN1KMT2AMAPTGAAMAPK1 | |
| SCHEMBL22817 | 0.67 | MAPT (0.56) | MEN1KMT2AMAPTGAAMAPK1 | |
| SCHEMBL14453287 | 0.66 | MAPT (0.52) | MAPTGAAMAPK1SMN1; SMN2TSHR | |
| SCHEMBL17745050 | 0.66 | CASP3 (0.37) | MEN1APAF1CASP3KMT2APAX8 | |
| SCHEMBL11682921 | 0.66 | MAPT (0.45) | MAPTGAAMAPK1SMN1; SMN2TSHR | |
| SCHEMBL6787147 | 0.66 | ALDH1A1 (0.55) | KMT2AMAPTGAAMAPK1TSHR | |
| SCHEMBL11383936 | 0.65 | MEN1 (0.39) | MEN1APAF1CASP3KMT2APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2333018-A1 | Dying composition comprising a particular disulfide dye and process of dying keratinous fibres with this dye | L'Oréal (FR) | 2011-06-15 | — | — | EP | disclosed |