Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392957 | 0.80 | MAPT (0.40) | MAPTGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL123696 | 0.79 | MAPT (0.39) | MAPTGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15020242 | 0.70 | KDR (0.34) | MAPTSMN1; SMN2RAB9AALDH1A1KDR | |
| SCHEMBL15039274 | 0.68 | KDR (0.38) | KDRMEN1KMT2AAPAF1CASP3 | |
| SCHEMBL15020967 | 0.66 | MAPT (0.33) | MAPTGAARAB9AALDH1A1KDR | |
| SCHEMBL29763992 | 0.66 | MAPT (0.56) | MAPTGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL22817 | 0.66 | MAPT (0.56) | MAPTGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL14453287 | 0.65 | MAPT (0.52) | MAPTGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15039377 | 0.64 | KDR (0.36) | MAPTALDH1A1KDRHTTTSHR | |
| SCHEMBL9398336 | 0.63 | MAPT (0.50) | MAPTGAAALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061880-A1 | METHOD FOR DYEING KERATIN FIBRES STARTING FROM ISATIN AND FROM POWDER AND/OR DYE EXTRACT OF INDIGO-PRODUCING PLANTS | L'OREAL (FR) | 2023-04-20 | — | — | WO | disclosed |
| US-11117864-B2 | Use for dyeing keratin fibers of a compound of azomethine type bearing a quinoline-derived unit | L'OREAL (FR) | 2021-09-14 | — | — | US | disclosed |
| US-11007131-B2 | Dyeing composition comprising a direct dye of triarylmethane structure, and a silicone | L'OREAL (FR) | 2021-05-18 | — | — | US | disclosed |
| US-11000464-B2 | Dyeing composition at acidic pH comprising a direct dye of triarylmethane structure | L'OREAL (FR) | 2021-05-11 | — | — | US | disclosed |
| EP-3393441-B1 | DYEING COMPOSITION COMPRISING A DIRECT DYE OF TRIARYLMETHANE STRUCTURE, AND A SILICONE | OREAL (FR) | 2021-01-20 | — | — | EP | disclosed |
| EP-3474814-B1 | A COMPOUND OF AZOMETHINE TYPE BEARING A QUINOLINE-DERIVED UNIT AND ITS USE FOR DYEING KERATIN FIBERS | OREAL (FR) | 2020-11-11 | — | — | EP | disclosed |
| US-20200308117-A1 | USE FOR DYEING KERATIN FIBERS OF A COMPOUND OF AZOMETHINE TYPE BEARING A QUINOLINE-DERIVED UNIT | L'OREAL (FR) | 2020-10-01 | — | — | US | disclosed |
| US-20200268629-A1 | DYEING COMPOSITION AT ACIDIC PH COMPRISING A DIRECT DYE OF TRIARYLMETHANE STRUCTURE | L'OREAL (FR) | 2020-08-27 | — | — | US | disclosed |
| US-20200261337-A1 | DYEING COMPOSITION COMPRISING A DIRECT DYE OF TRIARYLMETHANE STRUCTURE, AND A SILICONE | L'OREAL (FR) | 2020-08-20 | — | — | US | disclosed |
| WO-2019234193-A1 | PROCESS FOR DYEING AND/OR LIGHTENING KERATIN MATERIALS | L'OREAL (FR) | 2019-12-12 | — | — | WO | disclosed |
| EP-3389622-A1 | OXIDIZING COMPOSITION FOR TREATING KERATIN MATERIALS, COMPRISING A FATTY SUBSTANCE AND OXYALKYLENATED SURFACTANTS | L'Oréal (FR) | 2018-10-24 | — | — | EP | disclosed |
| US-20170348215-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING A PYRAZOLOPYRIDINE UNIT | L'OREAL (FR) | 2017-12-07 | — | — | US | disclosed |
| WO-2017103260-A1 | OXIDIZING COMPOSITION FOR TREATING KERATIN MATERIALS, COMPRISING A FATTY SUBSTANCE AND OXYALKYLENATED SURFACTANTS | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |
| US-20130266529-A1 | PROCESS FOR STRIPPING KERATIN FIBRES USING A COMPOSITION COMPRISING A SULFINIC ACID DERIVATIVE AND AN ACIDIC AQUEOUS COMPOSITION | L'OREAL (FR) | 2013-10-10 | — | — | US | disclosed |
| EP-2642976-A2 | PROCESS FOR STRIPPING KERATIN FIBRES USING A COMPOSITION COMPRISING A SULFINIC ACID DERIVATIVE AND AN ACIDIC AQUEOUS COMPOSITION | L'Oréal (FR) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012069599-A2 | PROCESS FOR STRIPPING KERATIN FIBRES USING A COMPOSITION COMPRISING A SULFINIC ACID DERIVATIVE AND AN ACIDIC AQUEOUS COMPOSITION | L'OREAL (FR) | 2012-05-31 | — | — | WO | disclosed |
| US-7892294-B2 | Method for dyeing keratin fibers using at least one compound of azomethine type comprising a pyrazolopyridine unit | L'OREAL S.A. (FR) | 2011-02-22 | — | — | US | disclosed |
| US-7887601-B2 | 2-[(3-{[2-amino-5-methyl-4-oxocyclohexa-2,5-dien-1-ylidene]amino}pyrazolo[1,5-a]pyridin-2-yl)amino]-N,N,N-trimethylethanaminium chloride; leuco dyes; along with an oxididizer; hair dyes; intensity | L'OREAL S.A. (FR) | 2011-02-15 | — | — | US | disclosed |
| US-20100275390-A1 | COMPOUNDS OF AZOMETHINE TYPE COMPRISING A CATIONIC PYRAZOLOPYRIDINE UNIT, FOR DYEING KERATIN FIBRES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | disclosed |
| US-20100275389-A1 | METHOD FOR DYEING KERATIN FIBERS USING AT LEAST ONE COMPOUND OF AZOMETHINE TYPE COMPRISING A PYRAZOLOPYRIDINE UNIT | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348215-A1 | USE FOR DYEING KERATIN FIBRES OF A COMPOUND OF AZOMETHINE TYPE BEARING A PYRAZOLOPYRIDINE UNIT | KRT18, TMPO, KMO | MAPT 9/4885GAA 4461/4885SMN1; SMN2 3452/4885 |
| US-11000464-B2 | Dyeing composition at acidic pH comprising a direct dye of triarylmethane structure | KRT18, TYR, DSG1 | MAPT 596/4885GAA 1235/4885SMN1; SMN2 4775/4885 |
| US-20100275390-A1 | COMPOUNDS OF AZOMETHINE TYPE COMPRISING A CATIONIC PYRAZOLOPYRIDINE UNIT, FOR DYEING KERATIN FIBRES | KRT18, TMPO, S100A4 | MAPT 24/4885GAA 4543/4885SMN1; SMN2 3279/4885 |
| US-20200308117-A1 | USE FOR DYEING KERATIN FIBERS OF A COMPOUND OF AZOMETHINE TYPE BEARING A QUINOLINE-DERIVED UNIT | KRT18, TUBB1, VIM | MAPT 30/4885GAA 3855/4885SMN1; SMN2 4601/4885 |
| US-11007131-B2 | Dyeing composition comprising a direct dye of triarylmethane structure, and a silicone | KRT18, TUBB1, TUBB3 | MAPT 359/4885GAA 3667/4885SMN1; SMN2 4665/4885 |
| US-11117864-B2 | Use for dyeing keratin fibers of a compound of azomethine type bearing a quinoline-derived unit | KRT18, TUBB1, VIM | MAPT 30/4885GAA 3855/4885SMN1; SMN2 4601/4885 |
| US-20200261337-A1 | DYEING COMPOSITION COMPRISING A DIRECT DYE OF TRIARYLMETHANE STRUCTURE, AND A SILICONE | KRT18, TUBB1, TUBB3 | MAPT 359/4885GAA 3667/4885SMN1; SMN2 4665/4885 |
| US-20200268629-A1 | DYEING COMPOSITION AT ACIDIC PH COMPRISING A DIRECT DYE OF TRIARYLMETHANE STRUCTURE | KRT18, TYR, DSG1 | MAPT 596/4885GAA 1235/4885SMN1; SMN2 4775/4885 |
| US-20130266529-A1 | PROCESS FOR STRIPPING KERATIN FIBRES USING A COMPOSITION COMPRISING A SULFINIC ACID DERIVATIVE AND AN ACIDIC AQUEOUS COMPOSITION | KRT18, DSG1, PRKX | MAPT 1452/4885GAA 4176/4885SMN1; SMN2 4036/4885 |
| US-20100275389-A1 | METHOD FOR DYEING KERATIN FIBERS USING AT LEAST ONE COMPOUND OF AZOMETHINE TYPE COMPRISING A PYRAZOLOPYRIDINE UNIT | KRT18, TMPO, KMO | MAPT 22/4885GAA 3913/4885SMN1; SMN2 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.