SCHEMBL19161629

SCHEMBL19161629

CC(C)(C)c1nc(-c2ccc3ccccc3c2)c2c(n1)sc1ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.38
▸ SRC P12931 6/20 0.35
▸ ABL1 P00519 3/20 0.35
▸ PIK3CD O00329 2/20 0.35
▸ PIK3CA P42336 2/20 0.35
▸ PIK3CB P42338 2/20 0.35
▸ PIK3CG P48736 2/20 0.35
▸ PRKDC P78527 2/20 0.35
▸ AR P10275 1/20 0.34
▸ CASR P41180 1/20 0.34
▸ HTR2B P41595 1/20 0.34
▸ HTR5A P47898 1/20 0.34
▸ RIPK2 O43353 1/20 0.33
▸ TNKS O95271 1/20 0.33
▸ TNKS2 Q9H2K2 1/20 0.33
▸ CSNK1D P48730 1/20 0.33
▸ MAPK11 Q15759 1/20 0.33
▸ MAPK14 Q16539 1/20 0.33
▸ MAPK8 P45983 1/20 0.33
▸ MAPK9 P45984 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19161963 0.86 ELANE (0.37) ELANETNKSTNKS2MAPK10TNF
SCHEMBL19161624 0.85 ELANE (0.39) ELANETNKSTNKS2MAPK10TNF
SCHEMBL23473798 0.85 ELANE (0.35) ELANEPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL19169963 0.83 ELANE (0.40) ELANESRCABL1PIK3CDPIK3CA
SCHEMBL19169782 0.82 S1PR5 (0.34) ELANEPRKDC
SCHEMBL17297623 0.81 ADK (0.37) ELANESRCABL1PIK3CDPIK3CA
SCHEMBL19161952 0.80 TNKS (0.45) SRCABL1PIK3CDPIK3CAPIK3CB
SCHEMBL19161965 0.79 KDM4E (0.37) ELANETNKSTNKS2
SCHEMBL19162693 0.79 KDM4E (0.37) ELANE
SCHEMBL25878070 0.79 ELANE (0.36) ELANETNKSTNKS2TNFNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 — — US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 — — US disclosed
US-10580998-B2 Nitrogen-containing condensed cyclic compound and organic light emitting device using same LG CHEM, LTD. (KR) 2020-03-03 — — US disclosed
US-20190173022-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2019-06-06 — — US disclosed
US-20170213984-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2017-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ELANE 874/4885SRC 2384/4885ABL1 3209/4885
US-10580998-B2 Nitrogen-containing condensed cyclic compound and organic light emitting device using same CRY1, NOS1, NOLC1 ELANE 2532/4885SRC 4402/4885ABL1 1147/4885
US-20190173022-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME CRY1, NOS1, NOLC1 ELANE 2532/4885SRC 4402/4885ABL1 1147/4885
US-20170213984-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME CRY1, NOS1, NOLC1 ELANE 2532/4885SRC 4402/4885ABL1 1147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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