SCHEMBL23473798

SCHEMBL23473798

CC(C)(C)c1nc(-c2cccc(-c3ccccc3)c2)c2c(n1)sc1ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.35
▸ MAPT P10636 3/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ HSD17B1 P14061 1/20 0.32
▸ HSD17B2 P37059 1/20 0.32
▸ LOXL2 Q9Y4K0 1/20 0.32
▸ PIM1 P11309 1/20 0.31
▸ PIM3 Q86V86 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ PTPN1 P18031 1/20 0.31
▸ SYK P43405 1/20 0.31
▸ PIK3CA P42336 2/20 0.31
▸ PI4KA P42356 1/20 0.31
▸ PI4KB Q9UBF8 1/20 0.31
▸ RORB Q92753 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19161963 0.91 ELANE (0.37) ELANEMAPTKDM4EALDH1A1CYP2C9
SCHEMBL19161624 0.91 ELANE (0.39) ELANEMAPTKDM4EALDH1A1HPGD
SCHEMBL19161629 0.85 ELANE (0.38) ELANEPIK3CATNKSTNKS2PIK3CD
SCHEMBL25878070 0.84 ELANE (0.36) ELANEMAPTKDM4EALDH1A1HPGD
SCHEMBL18017767 0.82 ADORA2A (0.40) ELANEKDM4EALDH1A1HPGDMEN1
SCHEMBL18370776 0.82 ADORA2A (0.40) ELANEKDM4EALDH1A1HPGDMEN1
SCHEMBL18370750 0.82 ADORA2A (0.40) ELANEKDM4EALDH1A1HPGDMEN1
SCHEMBL18370795 0.82 ADORA2A (0.40) ELANEKDM4EALDH1A1HPGDMEN1
SCHEMBL18017810 0.82 ADORA2A (0.40) ELANEKDM4EALDH1A1HPGDMEN1
SCHEMBL18370715 0.82 ADORA2A (0.43) ELANEMAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11725138-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-08-15 — — US disclosed
US-11725138-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-08-15 — — US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 — — US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 — — US disclosed
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-11-10 — — US disclosed
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-06-02 — — US disclosed
US-20220045281-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-10 — — US disclosed
US-20210320263-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-14 — — US disclosed
US-20210175433-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-06-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, SOD1, NECTIN4 ELANE 514/4885MAPT 3004/4885KDM4E 2591/4885
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM ELANE 874/4885MAPT 1215/4885KDM4E 3255/4885
US-20220045281-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, ICOSLG, OR10J3 ELANE 728/4885MAPT 915/4885KDM4E 1059/4885
US-11725138-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same OR10J3, ICOSLG, TRPM4 ELANE 871/4885MAPT 1106/4885KDM4E 1072/4885
US-20210175433-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, ICOSLG, TRPM4 ELANE 871/4885MAPT 1106/4885KDM4E 1072/4885
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, OR10J3 ELANE 1219/4885MAPT 2475/4885KDM4E 1293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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