Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.35 |
| ▸ | CTSK | P43235 | 11/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17447489 | 0.84 | MEN1 (0.41) | CTSSCTSKCTSLCTSBMCL1 | |
| SCHEMBL19169555 | 0.83 | MAPT (0.34) | MCL1 | |
| SCHEMBL20220995 | 0.81 | CTSS (0.42) | CTSSCTSKCTSLMCL1 | |
| SCHEMBL17447513 | 0.79 | CTSS (0.40) | CTSSCTSKCTSLCTSB | |
| SCHEMBL27381292 | 0.77 | RIPK1 (0.35) | MCL1 | |
| SCHEMBL8691068 | 0.76 | CTSK (0.40) | CTSSCTSKCTSLCTSBMCL1 | |
| SCHEMBL6019293 | 0.74 | CTSS (0.39) | CTSSCTSKCTSLCTSBMCL1 | |
| SCHEMBL19169711 | 0.73 | MCL1 (0.38) | CTSSCTSKCTSLCTSBMCL1 | |
| SCHEMBL19169716 | 0.73 | CNR1 (0.33) | — | |
| SCHEMBL19169785 | 0.73 | CNR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | OPRL1, OPRM1, OPRD1 | CTSS 4051/4885CTSK 4551/4885CTSL 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.