Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468750 | 0.84 | SMN1; SMN2 (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL468749 | 0.84 | SMN1; SMN2 (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Hydrogen Sulfide SCHEMBL27584727 | 0.82 | SMN1; SMN2 (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Methane SCHEMBL5044803 | 0.82 | SMN1; SMN2 (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Methane SCHEMBL5044798 | 0.82 | SMN1; SMN2 (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetic Acid SCHEMBL27748313 | 0.82 | SMN1; SMN2 (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL14111179 | 0.81 | NFKB1 (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL12661040 | 0.81 | NFKB1 (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL5812827 | 0.80 | THRB (0.41) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL17623530 | 0.80 | KDM4E (0.41) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718765-B1 | Process for preparation of optically pure N-substituted-3-methoxypropionic acid derivatives | SCI PHARMTECH, INC. (TW) | 2017-08-01 | — | — | US | disclosed |