SCHEMBL468750

SCHEMBL468750

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nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.59
KDM4E B2RXH2 1/20 0.59
MAPT P10636 1/20 0.59
THRB P10828 1/20 0.59
ALOX15 P16050 1/20 0.59
NFKB1 P19838 1/20 0.59
PTGS2 P35354 1/20 0.59
THPO P40225 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
ALDH1A1 P00352 1/20 0.57
GNPAT O15228 2/20 0.47
TGFBR1 P36897 3/20 0.44
FOLH1 Q04609 6/20 0.43
NAALAD2 Q9Y3Q0 4/20 0.43
RIMKLA Q8IXN7 1/20 0.43
ALB P02768 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468749 1.00 SMN1; SMN2 (0.59) SMN1; SMN2KDM4EMAPTTHRBALOX15
Hydrogen Sulfide SCHEMBL27584727 0.98 SMN1; SMN2 (0.57) SMN1; SMN2KDM4EMAPTTHRBALOX15
Acetic Acid SCHEMBL27748313 0.98 SMN1; SMN2 (0.57) SMN1; SMN2KDM4EMAPTTHRBALOX15
Methane SCHEMBL5044798 0.98 SMN1; SMN2 (0.57) SMN1; SMN2KDM4EMAPTTHRBALOX15
Methane SCHEMBL5044803 0.98 SMN1; SMN2 (0.57) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL6841658 0.85 SMN1; SMN2 (0.53) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL6896498 0.85 SMN1; SMN2 (0.53) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL19183299 0.84 KDM4E (0.45) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL16745724 0.84 GNPAT (0.62) SMN1; SMN2KDM4EMAPTTHRBALOX15
SCHEMBL7719184 0.84 SMN1; SMN2 (0.52) SMN1; SMN2KDM4EMAPTTHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119799606-A Recombinant escherichia coli for producing heme and derivative compound thereof and preparation method thereof 微元合成生物技术(北京)有限公司 2025-04-11 CN claimed
EP-3504318-B1 METHOD OF IMPROVING METHYLTRANSFERASE ACTIVITY UNIV DANMARKS TEKNISKE (DK) 2025-04-09 EP claimed
CN-119555822-A Urine metabolism marker composition for diagnosis of cancer seeds of pan-cancer, screening method and application 哈尔滨脉图精准技术有限公司 2025-03-04 CN claimed
WO-2024179537-A1 METHOD FOR DIRECTLY PREPARING L-GLUFOSINATE FROM L-HOMOSERINE 湖南利尔生物科技有限公司 2024-09-06 WO claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
EP-4182300-A1 IMPROVED METHOD FOR SYNTHESISING FUNCTIONALISED MERCAPTANS ARKEMA FRANCE (FR) 2023-05-24 EP claimed
US-20230080311-A1 Method of improving methyltransferase activity DANMARKS TEKNISKE UNIVERSITET (DK) 2023-03-16 US claimed
CN-115725537-A Aspartokinase mutant and application thereof in producing L-homoserine 中国科学院天津工业生物技术研究所 2023-03-03 CN claimed
EP-2751276-B1 PREPARATION PROCESS OF L-METHIONINE ARKEMA FRANCE (FR) 2023-01-25 EP claimed
US-11124813-B2 N-acetyl homoserine EVONIK OPERATIONS GMBH (DE) 2021-09-21 US claimed
EP-1639994-A2 Topical composition comprising N-acetylaldosamines or N-acetylamino acids Yu, Ruey J., Dr. (US) 2006-03-29 EP claimed
US-20060063827-A1 Systemic administration of therapeutic amino acids and N-acetylamino acids YU RUEY J 2006-03-23 US claimed
EP-1633851-A2 METHODS AND COMPOSITIONS FOR AMINO ACID PRODUCTION Microbia, Inc. (US) 2006-03-15 EP claimed
US-20050255568-A1 Methods and compositions for amino acid production NOVUS INTERNATIONAL, INC. 2005-11-17 US claimed
EP-1570840-A2 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2005-09-07 EP claimed
US-20050171194-A1 Enlargement of mucocutaneous or cutaneous organs and sites with topical compositions YU RUEY J (US) 2005-08-04 US claimed
WO-2004108894-A2 METHODS AND COMPOSITIONS FOR AMINO ACID PRODUCTION MICROBIA, INC. (US) 2004-12-16 WO claimed
US-6524593-B1 Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails TRISTRATA, INC. 2003-02-25 US claimed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US claimed
WO-2000040217-B1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-10-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11124813-B2 N-acetyl homoserine ACAT2, PSAT1, ACSS2 SMN1; SMN2 4611/4885KDM4E 3791/4885MAPT 4029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.