SCHEMBL10061335

SCHEMBL10061335

CCCCc1ccc(CNC(=O)c2c(Cl)c(CC)nn2C)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.57
RAB9A P51151 7/20 0.57
SMN1; SMN2 Q16637 5/20 0.57
KMT2A Q03164 2/20 0.57
GALR3 O60755 1/20 0.57
NR2F2 P24468 1/20 0.57
NPC1 O15118 5/20 0.49
ATM Q13315 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
POLB P06746 1/20 0.49
NR1I2 O75469 1/20 0.47
AHR P35869 1/20 0.47
MAPT P10636 3/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.44
HTT P42858 1/20 0.44
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
ALPL P05186 1/20 0.43
ALPI P09923 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14188833 0.97 LMNA (0.56) LMNARAB9ASMN1; SMN2KMT2AGALR3
SCHEMBL14262522 0.90 LMNA (0.54) LMNARAB9ASMN1; SMN2KMT2AGALR3
SCHEMBL19185953 0.90 LMNA (0.54) LMNARAB9ASMN1; SMN2KMT2AGALR3
SCHEMBL13760625 0.89 RAB9A (0.56) LMNARAB9ASMN1; SMN2KMT2AGALR3
SCHEMBL8077552 0.88 LMNA (0.54) LMNARAB9ASMN1; SMN2KMT2AGALR3
SCHEMBL10405134 0.87 LMNA (0.50) LMNARAB9ASMN1; SMN2KMT2AGALR3
SCHEMBL15220664 0.87 LMNA (0.60) LMNARAB9ASMN1; SMN2KMT2AGALR3
SCHEMBL8069793 0.84 LMNA (0.56) LMNARAB9ASMN1; SMN2KMT2AGALR3
Tebufenpyrad SCHEMBL26848 0.84 LMNA (0.59) LMNARAB9ASMN1; SMN2KMT2AGALR3
Tebufenpyrad SCHEMBL8407688 0.84 LMNA (0.59) LMNARAB9ASMN1; SMN2KMT2AGALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190127333-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING LANTHEUS MEDICAL IMAGING, INC. (US) 2019-05-02 US disclosed
US-8299036-B2 Active agent combinations with insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2012-10-30 US disclosed
US-20120010076-A1 ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERITIES BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed
WO-2011134964-A1 SYNERGISTIC ACTIVE SUBSTANCE COMBINATIONS BAYER CROPSCIENCE AG (DE) 2011-11-03 WO disclosed
US-8044085-B2 Active agent combinations with insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2011-10-25 US disclosed
US-20100311677-A1 Active Ingredient Combinations Having Insecticidal and Acaricidal Properties BAYER CROPSCIENCE AG (DE) 2010-12-09 US disclosed
US-20100204167-A1 ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2010-08-12 US disclosed
US-20100197737-A1 ACTIVE AGENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2010-08-05 US disclosed
US-20100168042-A1 ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2010-07-01 US disclosed
US-20090286788-A1 Active agent combinations with insecticidal and acaricidal properties BAYER INTELLECTUAL PROPERTY GMBH (DE) 2009-11-19 US disclosed
WO-2009135613-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-11-12 WO disclosed
US-7585887-B2 Active agent combinations with insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2009-09-08 US disclosed
WO-2009043442-A1 ACTIVE AGENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2009-04-09 WO disclosed
WO-2009039951-A2 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2009-04-02 WO disclosed
EP-2039248-A1 Active agent combinations with insecticide and acaricide properties Bayer CropScience AG (DE) 2009-03-25 EP disclosed
US-20090054470-A1 USE OF MITOCHONDRIAL ELECTRON TRANSPORT INHIBITORS TO CONTROL FOULING ORGANISMS JANSSEN PHARMACEUTICA N.V. (BE) 2009-02-26 US disclosed
EP-1982594-A1 Active agent combinations with insecticidal and acaricidal properties Bayer CropScience AG (DE) 2008-10-22 EP disclosed
US-20080027114-A1 Active Agent Combinations with Insecticidal and Acaricidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2008-01-31 US disclosed
WO-2008006513-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2008-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100197737-A1 ACTIVE AGENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES ACHE, AADAC, AMY1A LMNA 3102/4885RAB9A 819/4885SMN1; SMN2 1820/4885
US-20080027114-A1 Active Agent Combinations with Insecticidal and Acaricidal Properties AADAC, ACAA2, AAAS LMNA 3255/4885RAB9A 2874/4885SMN1; SMN2 3295/4885
US-20190127333-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING TNNI3, TNNT2, FABP3 LMNA 3348/4885RAB9A 3276/4885SMN1; SMN2 2969/4885
US-20120010076-A1 ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERITIES ACAA2, ACHE, AADAC LMNA 1985/4885RAB9A 1065/4885SMN1; SMN2 3267/4885
US-20090286788-A1 Active agent combinations with insecticidal and acaricidal properties ACAA2, ACHE, AADAC LMNA 2265/4885RAB9A 1120/4885SMN1; SMN2 2823/4885
US-20090054470-A1 USE OF MITOCHONDRIAL ELECTRON TRANSPORT INHIBITORS TO CONTROL FOULING ORGANISMS MCU, IMMT, SQOR LMNA 4329/4885RAB9A 1597/4885SMN1; SMN2 4590/4885
US-20100204167-A1 ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES ACHE, ACAT2, ACAT1 LMNA 3101/4885RAB9A 618/4885SMN1; SMN2 620/4885
US-20100168042-A1 ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES AADAC, ACAA2, AAAS LMNA 3255/4885RAB9A 2874/4885SMN1; SMN2 3295/4885
US-20100311677-A1 Active Ingredient Combinations Having Insecticidal and Acaricidal Properties ACHE, ACAT2, ACAT1 LMNA 2893/4885RAB9A 253/4885SMN1; SMN2 528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.