Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | TTR | P02766 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130509 | 0.87 | KDM4E (0.61) | MEN1MAPTKMT2AKDM4ECYP3A4 | |
| SCHEMBL1808386 | 0.86 | MEN1 (0.84) | MEN1MAPTKMT2AKDM4ECYP3A4 | |
| SCHEMBL1486831 | 0.86 | MEN1 (0.73) | MEN1MAPTKMT2AKDM4ECYP3A4 | |
| SCHEMBL1808387 | 0.86 | MEN1 (0.84) | MEN1MAPTKMT2AKDM4ECYP3A4 | |
| SCHEMBL1486827 | 0.86 | MEN1 (0.73) | MEN1MAPTKMT2AKDM4ECYP3A4 | |
| SCHEMBL18648497 | 0.86 | LMNA (0.63) | MEN1MAPTKMT2AKDM4ECYP3A4 | |
| SCHEMBL19237131 | 0.84 | PTGS2 (0.71) | MEN1MAPTKMT2AKDM4ECYP3A4 | |
| SCHEMBL6847961 | 0.82 | KDM4E (0.81) | MEN1MAPTKMT2AKDM4ECYP3A4 | |
| SCHEMBL1810217 | 0.82 | KDM4E (0.81) | MEN1MAPTKMT2AKDM4ECYP3A4 | |
| SCHEMBL23393767 | 0.81 | LMNA (0.69) | MEN1MAPTKMT2AKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170216272-A1 | COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216272-A1 | COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS | FABP4, GPR119, SIRT1 | MEN1 4290/4885MAPT 2433/4885KMT2A 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.