Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19199769 | 1.00 | PIN1 (0.47) | PIN1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL19199568 | 0.86 | KMT2A (0.45) | TSHRKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL19199783 | 0.86 | KMT2A (0.45) | TSHRKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL19199856 | 0.85 | KMT2A (0.51) | TSHRKMT2ATDP1LMNAMAPT | |
| SCHEMBL19200097 | 0.85 | KMT2A (0.51) | TSHRKMT2ATDP1LMNAMAPT | |
| SCHEMBL19199740 | 0.83 | LMNA (0.49) | TSHRKMT2AMEN1NPC1LMNA | |
| SCHEMBL19199749 | 0.83 | POLB (0.49) | TSHRKMT2AMEN1NPC1ATM | |
| SCHEMBL19199827 | 0.83 | LMNA (0.49) | TSHRKMT2AMEN1NPC1LMNA | |
| SCHEMBL19200664 | 0.83 | POLB (0.49) | TSHRKMT2AMEN1NPC1ATM | |
| SCHEMBL19199833 | 0.83 | LMNA (0.64) | LMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927355-B2 | Method for producing an organosilicon product | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-02-23 | — | — | US | disclosed |
| US-20170218346-A1 | Heme Protein Catalysts for Carbon-Silicon Bond Formation In Vitro and In Vivo | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927355-B2 | Method for producing an organosilicon product | HMOX2, HMOX1, HMBS | PIN1 57/4885TSHR 4561/4885KMT2A 3909/4885 |
| US-20170218346-A1 | Heme Protein Catalysts for Carbon-Silicon Bond Formation In Vitro and In Vivo | HMOX2, HMOX1, HCCS | PIN1 79/4885TSHR 4669/4885KMT2A 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.