Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19194689 | 0.85 | HCRTR2 (0.42) | HCRTR2FFAR1TERTCYP1A2CYP2D6 | |
| SCHEMBL19195119 | 0.84 | HCRTR2 (0.41) | HCRTR2FFAR1TERTCYP1A2CYP2D6 | |
| SCHEMBL13981216 | 0.77 | HTR1A (0.51) | HCRTR2FFAR1HTR2CHTR1AHTR1D | |
| SCHEMBL1723161 | 0.76 | TERT (0.38) | HCRTR2FFAR1TERTCYP1A2CYP2D6 | |
| SCHEMBL758865 | 0.76 | PNMT (0.47) | HCRTR2TERTCHRNB2CHRNA4CHRNB4 | |
| SCHEMBL9749380 | 0.76 | DRD3 (0.50) | CYP1A2CYP2D6CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL31136214 | 0.75 | HCRTR2 (0.44) | HCRTR2TERTCYP1A2CYP2D6CHRNB2 | |
| SCHEMBL24090506 | 0.73 | HTR2B (0.55) | HCRTR2HTR1AHTR2B | |
| SCHEMBL17107572 | 0.73 | PNMT (0.45) | HCRTR2FFAR1TERTCHRNB2CHRNA4 | |
| SCHEMBL21810954 | 0.71 | HCRTR2 (0.43) | HCRTR2FFAR1TERTCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170216259-A1 | COMPOSITIONS AND METHODS FOR TARGETING RECEPTORS EXPRESSED IN THE GUT | SENSOR PHARMACEUTICALS, INC. | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216259-A1 | COMPOSITIONS AND METHODS FOR TARGETING RECEPTORS EXPRESSED IN THE GUT | FABP2, GPBAR1, NR1H4 | HCRTR2 166/4885FFAR1 55/4885TERT 4515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.