Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631905 | 1.00 | FFAR1 (0.43) | FFAR1FFAR4KDM4EHTR1ANFE2L2 | |
| SCHEMBL7480447 | 0.94 | KDM4E (0.41) | FFAR1FFAR4KDM4ENFE2L2PTGS1 | |
| SCHEMBL29559341 | 0.83 | FFAR1 (0.42) | FFAR1FFAR4KDM4ESLC6A4LMNA | |
| SCHEMBL28665291 | 0.82 | ALDH1A1 (0.34) | KDM4ESLC6A4MAPK1MEN1KMT2A | |
| SCHEMBL1919969 | 0.82 | LMNA (0.54) | KDM4EAGTR1LMNACYP1A2 | |
| SCHEMBL23363940 | 0.81 | ADRA1D (0.39) | SLC6A4 | |
| SCHEMBL12435311 | 0.81 | FFAR1 (0.41) | FFAR1FFAR4LMNACYP1A2MEN1 | |
| SCHEMBL12655428 | 0.81 | HRH4 (0.32) | FFAR1CYP1A2 | |
| SCHEMBL4356588 | 0.81 | PKM (0.49) | KDM4ELMNACYP1A2MAPK1MEN1 | |
| SCHEMBL31357943 | 0.81 | ADRA1D (0.39) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761410-B | Pyrrolopyrimidinone compounds and application thereof | 广州必贝特医药股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-114761410-A | Pyrrolopyrimidinone compounds and application thereof | 广州必贝特医药股份有限公司 | 2022-07-15 | — | — | CN | disclosed |