Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18380803 | 0.86 | CARM1 (0.46) | CARM1PRMT6PRMT1PRMT8HRH3 | |
| SCHEMBL10032113 | 0.81 | CARM1 (0.52) | CARM1PRMT6PRMT1PRMT8HRH3 | |
| SCHEMBL18007378 | 0.79 | ACHE (0.41) | CARM1PRMT6PRMT1PRMT8HRH3 | |
| SCHEMBL18403180 | 0.79 | CARM1 (0.39) | CARM1PRMT6PRMT8HRH3MAOB | |
| SCHEMBL21214412 | 0.78 | HRH3 (0.48) | HRH3MAOB | |
| SCHEMBL19226691 | 0.78 | HRH3 (0.48) | HRH3MAOB | |
| SCHEMBL19200880 | 0.78 | CARM1 (0.48) | CARM1PRMT6PRMT1PRMT8HRH3 | |
| SCHEMBL24800863 | 0.77 | CACNA1I (0.31) | SIGMAR1 | |
| SCHEMBL19573431 | 0.77 | RAB9A (0.38) | HTTSIGMAR1 | |
| SCHEMBL13948657 | 0.77 | HRH3 (0.42) | CARM1PRMT6PRMT8HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170216252-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | SIMON FRASER UNIVERSITY (CA) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216252-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | PDK1, PDK3, PDK2 | CARM1 2906/4885PRMT6 2176/4885PRMT1 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.