Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032113 | 0.83 | CARM1 (0.52) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL19200875 | 0.78 | CARM1 (0.47) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL1515168 | 0.77 | CARM1 (0.50) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL20234635 | 0.77 | CARM1 (0.65) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL18380803 | 0.76 | CARM1 (0.46) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL23808983 | 0.76 | RAB9A (0.39) | SIGMAR1HRH3 | |
| SCHEMBL12245557 | 0.75 | SIGMAR1 (0.50) | CARM1PRMT6PRMT1PRMT8POLB | |
| SCHEMBL22017110 | 0.74 | SMN1; SMN2 (0.50) | SIGMAR1 | |
| SCHEMBL13602668 | 0.73 | SIGMAR1 (0.49) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL5245927 | 0.73 | CARM1 (0.56) | CARM1PRMT6PRMT1PRMT8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170216252-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | SIMON FRASER UNIVERSITY (CA) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216252-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES AND METHODS | PDK1, PDK3, PDK2 | CARM1 2906/4885PRMT6 2176/4885PRMT1 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.