SCHEMBL19202270

SCHEMBL19202270

O=C(O)Cc1cc(CC(=O)O)cc(C(=O)c2ccccc2)c1

nearest known ligand 0.76

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
AKR1B1 P15121 2/20 0.56
SRD5A2 P31213 4/20 0.54
ATM Q13315 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ABCC4 O15439 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 1/20 0.48
PTGS1 P23219 1/20 0.48
HTT P42858 1/20 0.48
PTGS2 P35354 1/20 0.47
KMT2A Q03164 2/20 0.47
HPGD P15428 1/20 0.47
PBRM1 Q86U86 1/20 0.46
MEN1 O00255 1/20 0.45
GABRA1 P14867 1/20 0.44
GABRB1 P18505 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31119235 0.91 PTGS2 (0.60) ALDH1A1AKR1B1SRD5A2ATMTDP1
SCHEMBL19202480 0.89 AKR1B1 (0.48) ALDH1A1AKR1B1SRD5A2TDP1ABCC4
SCHEMBL19202271 0.89 AKR1B1 (0.52) AKR1B1SRD5A2ATMTDP1L3MBTL1
SCHEMBL512838 0.86 ATM (0.63) ALDH1A1AKR1B1SRD5A2ATMTDP1
Benzophenone SCHEMBL8820654 0.85 AKR1B1 (0.77) ALDH1A1AKR1B1SRD5A2ATMTDP1
Methane SCHEMBL11262863 0.85 ATM (0.61) ALDH1A1AKR1B1SRD5A2ATMTDP1
Hydrochloric Acid SCHEMBL11844165 0.85 ATM (0.61) ALDH1A1AKR1B1SRD5A2ATMTDP1
SCHEMBL1415906 0.83 SRD5A2 (0.73) ALDH1A1AKR1B1SRD5A2ATMTDP1
Methane SCHEMBL11257402 0.83 ATM (0.59) ALDH1A1AKR1B1SRD5A2ATMTDP1
SCHEMBL20083089 0.82 SRD5A2 (0.62) ALDH1A1SRD5A2ATMTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11548984-B2 Light- or heat-curing method and curable resin composition FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2023-01-10 US disclosed
US-10774062-B2 Photocuring method, compound and composition used therein FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-09-15 US disclosed
US-20200123324-A1 LIGHT- OR HEAT-CURING METHOD AND CURABLE RESIN COMPOSITION FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-04-23 US disclosed
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-02-21 US disclosed
WO-2017131047-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN 和光純薬工業株式会社 2017-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190055210-A1 PHOTOCURING METHOD, COMPOUND AND COMPOSITION USED THEREIN ESD, TMT1A, PAM ALDH1A1 23/4885AKR1B1 1305/4885SRD5A2 1004/4885
US-10774062-B2 Photocuring method, compound and composition used therein ESD, TMT1A, PAM ALDH1A1 23/4885AKR1B1 1305/4885SRD5A2 1004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.