Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 13/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 12/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.50 |
| ▸ | CCND3 | P30281 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.42 |
| ▸ | CDK1 | P06493 | 6/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17328441 | 0.77 | CDK2 (0.43) | CDK2CCNE2CCNE1CCND3HDAC3 | |
| SCHEMBL13827907 | 0.72 | CDK2 (0.44) | CDK2CCNE2CCNE1CCND3CCNB2 | |
| SCHEMBL13616184 | 0.72 | CDK2 (0.48) | CDK2CCNE2CCNE1CCND3HDAC3 | |
| SCHEMBL10268216 | 0.72 | CDK2 (0.46) | CDK2CCNE2CCNE1CCND3CCNB2 | |
| SCHEMBL5724749 | 0.70 | CDK2 (0.45) | CDK2CCNE2CCNE1CCND3HDAC3 | |
| SCHEMBL3719448 | 0.69 | RXRA (0.51) | CDK2CCNE2CCNE1CCND3HDAC3 | |
| SCHEMBL3712368 | 0.69 | CDK2 (0.42) | CDK2CCNE2CCNE1CCND3HDAC3 | |
| SCHEMBL10150924 | 0.68 | CCNE1 (0.41) | CDK2CCNE1HPGD | |
| SCHEMBL19825530 | 0.67 | CDK2 (0.43) | CDK2CCNE2CCNE1CCND3CCNB2 | |
| SCHEMBL20583110 | 0.67 | CDK2 (0.40) | CDK2CCNE2CCNE1CCND3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218000-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170218000-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | MAP3K6, PIK3CA, MAP3K20 | CDK2 59/4885CCNE2 1101/4885CCNE1 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.