Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.46 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15219332 | 0.93 | HTT (0.61) | HTTLMNAL3MBTL3L3MBTL1HPGD | |
| SCHEMBL24204687 | 0.89 | HTT (0.56) | HTTLMNAL3MBTL3L3MBTL1HPGD | |
| SCHEMBL20160117 | 0.86 | HTT (0.57) | HTTLMNAL3MBTL3L3MBTL1HPGD | |
| SCHEMBL24352372 | 0.86 | LMNA (0.60) | HTTLMNAL3MBTL3L3MBTL1HPGD | |
| SCHEMBL8191261 | 0.86 | L3MBTL3 (0.57) | HTTLMNAL3MBTL3L3MBTL1HPGD | |
| SCHEMBL2075903 | 0.84 | HTT (0.81) | HTTLMNAHPGDCHRNB2CHRNA3 | |
| SCHEMBL24334506 | 0.82 | HSD11B1 (0.56) | HTTLMNAL3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL27932674 | 0.82 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1HRH3ALDH1A1ACACB | |
| SCHEMBL26042842 | 0.82 | L3MBTL3 (0.54) | HTTLMNAL3MBTL3L3MBTL1HRH3 | |
| SCHEMBL24207499 | 0.82 | CHRNB2 (0.51) | HTTLMNAL3MBTL3L3MBTL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218000-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170218000-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | MAP3K6, PIK3CA, MAP3K20 | HTT 4878/4885LMNA 4121/4885L3MBTL3 4049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.