SCHEMBL19206312

SCHEMBL19206312

Oc1cc(O)c(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.53
▸ KMT2A Q03164 4/20 0.53
▸ NTSR1 P30989 1/20 0.53
▸ ADORA2A P29274 3/20 0.47
▸ ADORA1 P30542 3/20 0.47
▸ ADORA3 P0DMS8 2/20 0.47
▸ ADORA2B P29275 2/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ ALOX5 P09917 1/20 0.45
▸ MAPT P10636 3/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ ESR1 P03372 2/20 0.44
▸ ESR2 Q92731 2/20 0.44
▸ POLB P06746 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ BACE1 P56817 1/20 0.41
▸ NQO1 P15559 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19240516 0.84 NPC1 (0.49) MEN1KMT2ANTSR1ADORA3TSHR
SCHEMBL19240504 0.83 MEN1 (0.45) MEN1KMT2ANTSR1ADORA2AADORA1
SCHEMBL22373613 0.82 NQO1 (0.50) MEN1KMT2AALOX15TSHRL3MBTL1
SCHEMBL19206304 0.80 ALDH1A1 (0.49) MEN1KMT2ANTSR1ADORA2AADORA1
SCHEMBL1243192 0.78 ALOX5 (0.64) MEN1KMT2ANTSR1ADORA2AADORA1
SCHEMBL29649804 0.78 ALOX5 (0.64) MEN1KMT2ANTSR1ADORA2AADORA1
SCHEMBL6563798 0.78 ALOX5 (0.64) MEN1KMT2ANTSR1ADORA2AADORA1
SCHEMBL29649729 0.78 ALOX5 (0.64) MEN1KMT2ANTSR1ADORA2AADORA1
SCHEMBL28583369 0.78 NQO1 (0.59) MEN1KMT2AALOX5MAPTALDH1A1
SCHEMBL19254052 0.77 CNR2 (0.47) L3MBTL1MAPTALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661421-B Ultraviolet absorber and synthetic resin composition 株式会社艾迪科 2020-07-07 — — CN disclosed
EP-3222693-B1 ULTRAVIOLET ABSORBER AND SYNTHETIC RESIN COMPOSITION ADEKA CORP (JP) 2019-04-17 — — EP disclosed
US-10144814-B2 Ultraviolet absorber and synthetic resin composition ADEKA CORPORATION (JP) 2018-12-04 — — US disclosed
EP-3222693-A1 ULTRAVIOLET ABSORBER AND SYNTHETIC RESIN COMPOSITION Adeka Corporation (JP) 2017-09-27 — — EP disclosed
US-20170233551-A1 ULTRAVIOLET ABSORBER AND SYNTHETIC RESIN COMPOSITION ADEKA CORPORATION (JP) 2017-08-17 — — US disclosed
US-20170233551-A1 ULTRAVIOLET ABSORBER AND SYNTHETIC RESIN COMPOSITION ADEKA CORPORATION (JP) 2017-08-17 — — US disclosed
US-20170233551-A1 ULTRAVIOLET ABSORBER AND SYNTHETIC RESIN COMPOSITION ADEKA CORPORATION (JP) 2017-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10144814-B2 Ultraviolet absorber and synthetic resin composition RER1, XRCC5, REV1 MEN1 2103/4885KMT2A 662/4885NTSR1 824/4885
US-20170233551-A1 ULTRAVIOLET ABSORBER AND SYNTHETIC RESIN COMPOSITION RER1, XRCC5, REV1 MEN1 2103/4885KMT2A 662/4885NTSR1 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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