SCHEMBL19206978

SCHEMBL19206978

Cn1c(-n2ccc3ccccc32)nc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.53
▸ ATM Q13315 1/20 0.50
▸ KDM4E B2RXH2 4/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ GAA P10253 1/20 0.47
▸ LMNA P02545 1/20 0.45
▸ MAPT P10636 3/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ RAB9A P51151 2/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ BIRC5 O15392 1/20 0.44
▸ CA12 O43570 2/20 0.44
▸ CA9 Q16790 2/20 0.44
▸ BRD4 O60885 1/20 0.44
▸ BRPF1 P55201 1/20 0.44
▸ KAT2B Q92831 1/20 0.44
▸ BRD9 Q9H8M2 1/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19206983 0.74 BIRC5 (0.38) ALDH1A1MAPTKMT2ABIRC5CA12
SCHEMBL20040486 0.72 SMN1; SMN2 (0.55) SMN1; SMN2ATMKDM4EALDH1A1GAA
SCHEMBL18292120 0.71 SMN1; SMN2 (0.50) SMN1; SMN2ATMKDM4EALDH1A1GAA
SCHEMBL13052919 0.71 BIRC5 (0.59) ALDH1A1MAPTKMT2ABIRC5CA12
SCHEMBL1171430 0.71 MEN1 (0.69) SMN1; SMN2ATMKDM4EALDH1A1GAA
SCHEMBL2186020 0.70 CDC7 (0.54) SMN1; SMN2KDM4EALDH1A1LMNAMAPT
SCHEMBL14259395 0.70 TERT (0.47) SMN1; SMN2KDM4EALDH1A1GAALMNA
SCHEMBL14685202 0.70 HSD11B1 (0.60) SMN1; SMN2ALDH1A1KMT2AMEN1
SCHEMBL14685207 0.70 HSD11B1 (0.60) SMN1; SMN2KDM4EALDH1A1LMNAMAPT
SCHEMBL11015614 0.70 KMT2A (0.49) SMN1; SMN2ATMKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11716898-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 — — US disclosed
US-11716898-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 — — US disclosed
US-11716898-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 — — US disclosed
US-20200295276-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2020-09-17 — — US disclosed
US-20200295276-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2020-09-17 — — US disclosed
US-10707427-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-07-07 — — US disclosed
US-10707427-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-07-07 — — US disclosed
US-20170237018-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-08-17 — — US disclosed
US-20170237018-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-08-17 — — US disclosed
US-20170237018-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170237018-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, JUND SMN1; SMN2 3257/4885ATM 4170/4885KDM4E 2637/4885
US-11716898-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND SMN1; SMN2 3257/4885ATM 4170/4885KDM4E 2637/4885
US-10707427-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND SMN1; SMN2 3775/4885ATM 3575/4885KDM4E 3150/4885
US-20200295276-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, JUND SMN1; SMN2 3257/4885ATM 4170/4885KDM4E 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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