Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19206978 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2ATMKMT2AMEN1KDM4E | |
| SCHEMBL11015614 | 0.71 | KMT2A (0.49) | SMN1; SMN2ATMKMT2AMEN1KDM4E | |
| SCHEMBL19449279 | 0.71 | GRM5 (0.43) | SMN1; SMN2PDE10AATMKMT2AMEN1 | |
| SCHEMBL20040486 | 0.69 | SMN1; SMN2 (0.55) | SMN1; SMN2ATMKMT2AMEN1KDM4E | |
| SCHEMBL1171430 | 0.69 | MEN1 (0.69) | SMN1; SMN2ATMKMT2AMEN1KDM4E | |
| SCHEMBL14685202 | 0.68 | HSD11B1 (0.60) | SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL14685207 | 0.68 | HSD11B1 (0.60) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL353890 | 0.67 | SMN1; SMN2 (0.63) | SMN1; SMN2ATMKMT2AMEN1KDM4E | |
| SCHEMBL1053419 | 0.67 | SMN1; SMN2 (1.00) | SMN1; SMN2ATMKMT2AMEN1KDM4E | |
| SCHEMBL4940460 | 0.67 | HSD11B1 (0.58) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2023-06-01 | — | — | US | disclosed |
| US-11584720-B2 | Photoredox-catalyzed direct C-H functionalization of arenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-02-21 | — | — | US | disclosed |
| US-10399947-B2 | Photoredox-catalyzed direct C—H functionalization of arenes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180148414-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2018-05-31 | — | — | US | disclosed |
| US-20180148414-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2018-05-31 | — | — | US | disclosed |
| WO-2016196816-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2016-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584720-B2 | Photoredox-catalyzed direct C-H functionalization of arenes | PPOX, AOC2, AOC3 | SMN1; SMN2 4719/4885PDE10A 2861/4885ATM 1304/4885 |
| US-10399947-B2 | Photoredox-catalyzed direct C—H functionalization of arenes | PPOX, AOC2, AOC3 | SMN1; SMN2 4726/4885PDE10A 2781/4885ATM 1330/4885 |
| US-20180148414-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | PPOX, AOC2, AOC3 | SMN1; SMN2 4719/4885PDE10A 2861/4885ATM 1304/4885 |
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | PPOX, AOC2, AOC3 | SMN1; SMN2 4719/4885PDE10A 2861/4885ATM 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.