Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207629 | 0.90 | MEN1 (0.47) | CSNK2A1USP2TSHRNPSR1KDM4E | |
| SCHEMBL19207409 | 0.84 | CSNK2A1 (0.61) | CSNK2A1USP2TSHRNPSR1KDM4E | |
| SCHEMBL19254333 | 0.83 | CSNK2A1 (0.47) | CSNK2A1USP2TSHRNPSR1KDM4E | |
| SCHEMBL19207434 | 0.83 | CSNK2A1 (0.47) | CSNK2A1USP2TSHRNPSR1KDM4E | |
| SCHEMBL19207439 | 0.82 | HDAC3 (0.47) | CSNK2A1USP2TSHRNPSR1KDM4E | |
| SCHEMBL19207423 | 0.78 | CSNK2A1 (0.49) | CSNK2A1USP2TSHRKDM4EHSD17B10 | |
| SCHEMBL19254587 | 0.77 | ALDH1A1 (0.41) | USP2TSHRNPSR1KDM4EHSD17B10 | |
| SCHEMBL19207635 | 0.77 | HDAC3 (0.60) | CSNK2A1USP2TSHRKDM4EHSD17B10 | |
| SCHEMBL19254586 | 0.76 | ADORA2B (0.41) | NPSR1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL19207493 | 0.73 | CSNK2A1 (0.65) | CSNK2A1USP2TSHRNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10765681-B2 | Purine compounds possessing anticancer activity | ACADEMIA SINICA (TW) | 2020-09-08 | — | — | US | disclosed |
| US-20180369249-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2018-12-27 | — | — | US | disclosed |
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180369249-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | NTPCR, PNP, NUDT1 | CSNK2A1 2675/4885KEAP1 1692/4885NFE2L2 1008/4885 |
| US-10765681-B2 | Purine compounds possessing anticancer activity | NTPCR, PNP, NUDT1 | CSNK2A1 2675/4885KEAP1 1692/4885NFE2L2 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.