Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207433 | 0.90 | CSNK2A1 (0.41) | MEN1KMT2AHTTMAPTCSNK2A1 | |
| SCHEMBL19207423 | 0.84 | CSNK2A1 (0.49) | MEN1KMT2ACSNK2A1LMNASMN1; SMN2 | |
| SCHEMBL19207493 | 0.83 | CSNK2A1 (0.65) | MEN1KMT2AHTTMAPTCSNK2A1 | |
| SCHEMBL19207407 | 0.81 | CSNK2A1 (0.49) | MEN1KMT2AHTTMAPTCSNK2A1 | |
| SCHEMBL19254587 | 0.80 | ALDH1A1 (0.41) | MAPTLMNANPSR1HDAC3HDAC4 | |
| SCHEMBL19254586 | 0.79 | ADORA2B (0.41) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL19207434 | 0.78 | CSNK2A1 (0.47) | MEN1KMT2AHTTMAPTCSNK2A1 | |
| SCHEMBL19254333 | 0.78 | CSNK2A1 (0.47) | MEN1KMT2AHTTMAPTCSNK2A1 | |
| SCHEMBL19207635 | 0.78 | HDAC3 (0.60) | MEN1KMT2ACSNK2A1LMNASMN1; SMN2 | |
| SCHEMBL19207409 | 0.74 | CSNK2A1 (0.61) | MEN1KMT2AHTTMAPTCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10765681-B2 | Purine compounds possessing anticancer activity | ACADEMIA SINICA (TW) | 2020-09-08 | — | — | US | disclosed |
| US-20180369249-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2018-12-27 | — | — | US | disclosed |
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180369249-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | NTPCR, PNP, NUDT1 | MEN1 1587/4885KMT2A 3206/4885HTT 3146/4885 |
| US-10765681-B2 | Purine compounds possessing anticancer activity | NTPCR, PNP, NUDT1 | MEN1 1587/4885KMT2A 3206/4885HTT 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.