Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GPR4 | P46093 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5124109 | 0.90 | TP53 (0.32) | TP53HTR2AHTR2CHTR2B | |
| SCHEMBL191733 | 0.86 | HTR2A (0.33) | TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL4061433 | 0.81 | ALDH1A1 (0.36) | TSHRTP53 | |
| SCHEMBL4061438 | 0.81 | ALDH1A1 (0.36) | TSHRTP53 | |
| SCHEMBL843383 | 0.78 | ALDH1A1 (0.32) | TP53 | |
| SCHEMBL192522 | 0.77 | TSHR (0.42) | TSHRMAPK1TP53HTR2AHTR2C | |
| SCHEMBL4056836 | 0.76 | TLR7 (0.40) | HTR2AHTR2CHTR2BTLR7 | |
| SCHEMBL2706466 | 0.73 | HRH1 (0.32) | TLR7 | |
| SCHEMBL10587340 | 0.73 | TLR7 (0.43) | TSHRMAPK1HTR2AHTR2BTLR7 | |
| SCHEMBL7231973 | 0.72 | AVPR1A (0.40) | TSHRTP53TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833827-B9 | PROCESS FOR PREPARING 2-METHYL-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C][1,5]NAPHTHYRIDIN-4-AMINE | MEDA AB (SE) | 2012-01-04 | — | — | EP | claimed |
| EP-1833827-B1 | PROCESS FOR PREPARING 2-METHYL-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C][1,5]NAPHTHYRIDIN-4-AMINE | MEDA AB (SE) | 2011-05-25 | — | — | EP | claimed |
| EP-1833827-B9 | PROCESS FOR PREPARING 2-METHYL-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C][1,5]NAPHTHYRIDIN-4-AMINE | MEDA AB (SE) | 2012-01-04 | — | — | EP | disclosed |
| EP-1833827-B1 | PROCESS FOR PREPARING 2-METHYL-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C][1,5]NAPHTHYRIDIN-4-AMINE | MEDA AB (SE) | 2011-05-25 | — | — | EP | disclosed |