Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841480 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNATP53CASP1HTT | |
| SCHEMBL4061433 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNATP53HTTSMN1; SMN2 | |
| SCHEMBL4061438 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNATP53HTTSMN1; SMN2 | |
| SCHEMBL191733 | 0.80 | HTR2A (0.33) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL192091 | 0.78 | TSHR (0.38) | TP53 | |
| SCHEMBL5124109 | 0.77 | TP53 (0.32) | LMNATP53 | |
| SCHEMBL842632 | 0.76 | TLR7 (0.42) | ALDH1A1LMNATP53 | |
| SCHEMBL4056836 | 0.71 | TLR7 (0.40) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL843176 | 0.71 | TLR7 (0.46) | — | |
| SCHEMBL5808831 | 0.70 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143270-B2 | 2-amino 1H-in-imidazo ring systems and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-03-27 | — | — | US | disclosed |