Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25418 | 0.92 | CTSS (0.44) | CTSLCTSSCTSBALDH1A1CYP3A4 | |
| SCHEMBL2688850 | 0.88 | CTSL (0.41) | CTSLCTSSCTSBALDH1A1CYP3A4 | |
| SCHEMBL1078249 | 0.87 | CTSS (0.42) | CTSLCTSSCTSBALDH1A1CYP3A4 | |
| SCHEMBL12246279 | 0.86 | CTSL (0.41) | CTSLCTSSCTSBALDH1A1CYP3A4 | |
| Acetic Acid SCHEMBL1046437 | 0.83 | NPFFR1 (0.45) | CTSLCTSSCTSBCTSKSMN1; SMN2 | |
| SCHEMBL2690074 | 0.83 | CTSL (0.40) | CTSLCTSSCTSBALDH1A1FKBP1A | |
| SCHEMBL4580794 | 0.82 | SYK (0.49) | CTSLCTSSCTSBALDH1A1FKBP1A | |
| SCHEMBL6368219 | 0.81 | CTSS (0.43) | CTSLCTSSCTSBALDH1A1FKBP1A | |
| SCHEMBL6368353 | 0.81 | LMNA (0.50) | CTSLCTSSCTSBALDH1A1MAPK1 | |
| SCHEMBL6368371 | 0.81 | ALDH1A1 (0.49) | CTSLCTSSCTSBALDH1A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709288-A | Phosphamide derivative and preparation method and application thereof | 四川海思科制药有限公司 | 2018-02-16 | — | — | CN | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |