Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547644 | 0.85 | CES2 (0.36) | HTR1ASLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL1322094 | 0.82 | CYP1A2 (0.45) | TAAR1KMT2ACYP1A2CYP2A6TDP1 | |
| SCHEMBL1703057 | 0.79 | TAS1R3 (0.45) | HTR1ASLC6A2TAAR1SLC6A4GAA | |
| SCHEMBL1918390 | 0.76 | HTR1A (0.41) | HTR1ASLC6A2TAAR1SLC6A4GAA | |
| SCHEMBL17607156 | 0.74 | CXCR5 (0.42) | HTR1ASLC6A2TAAR1SLC6A4GAA | |
| SCHEMBL19209996 | 0.74 | TAAR1 (0.41) | HTR1ASLC6A2TAAR1SLC6A4GAA | |
| SCHEMBL16545836 | 0.74 | KMT2A (0.40) | HTR1ASLC6A2TAAR1SLC6A4GAA | |
| SCHEMBL28855192 | 0.74 | HTR1A (0.40) | HTR1ASLC6A2TAAR1SLC6A4GAA | |
| SCHEMBL12129077 | 0.74 | L3MBTL1 (0.47) | HTR1ASLC6A2TAAR1SLC6A4GAA | |
| SCHEMBL15144694 | 0.74 | HTR1A (0.40) | HTR1ASLC6A2TAAR1SLC6A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018052903-A1 | RORγ MODULATORS | THE SCRIPPS RESEARCH INTITUTE (US) | 2018-03-22 | — | — | WO | disclosed |
| US-8426631-B2 | Fungicidal compounds, method for the production thereof, and use thereof to combat damaging fungi, and agents comprising the same | BASF SE (DE) | 2013-04-23 | — | — | US | disclosed |
| US-20100304966-A1 | Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same | BASF SE (DE) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100304966-A1 | Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same | CYP51A1, ERG28, CAT | HTR1A 4701/4885SLC6A2 4274/4885TAAR1 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.