Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 4/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13734870 | 0.90 | IKBKB (0.38) | RXRARXRBCTSAIKBKBRIPK2 | |
| SCHEMBL19210393 | 0.90 | MAPT (0.35) | CTSAIKBKBPPARDKDM4EALDH1A1 | |
| SCHEMBL13734542 | 0.88 | RIPK2 (0.38) | RXRARXRBCTSAIKBKBRIPK2 | |
| SCHEMBL19210474 | 0.84 | RXRA (0.34) | RXRARXRBCTSAFFAR1 | |
| SCHEMBL19210491 | 0.83 | AKR1C3 (0.38) | RXRARXRBCTSAIKBKBRIPK2 | |
| SCHEMBL19210419 | 0.83 | CTSA (0.34) | CTSA | |
| SCHEMBL19210449 | 0.83 | FFAR4 (0.36) | CTSAPPARDFFAR1PPARA | |
| SCHEMBL13734658 | 0.82 | PTPN1 (0.34) | RXRARXRBIKBKBPPARDFFAR1 | |
| SCHEMBL19210438 | 0.82 | IMPDH2 (0.33) | CTSA | |
| SCHEMBL19210395 | 0.81 | S1PR1 (0.36) | FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |