Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212206 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL19212266 | 0.85 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTSMN1; SMN2TDP1 | |
| SCHEMBL19212310 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL19212183 | 0.83 | RBP4 (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1873451 | 0.83 | TGM2 (0.65) | ALDH1A1MEN1KMT2AF13A1TGM2 | |
| SCHEMBL19212223 | 0.82 | MAPT (0.49) | ALDH1A1LMNAMAPTPOLBSMN1; SMN2 | |
| SCHEMBL20569350 | 0.81 | SLC6A9 (0.58) | SLC6A9ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL30890284 | 0.81 | LMNA (0.65) | SLC6A9ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL993182 | 0.81 | LMNA (0.65) | SLC6A9ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2390047 | 0.81 | TDP1 (0.67) | SLC6A9ALDH1A1LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |
| EP-3414252-A1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | Forma Therapeutics, Inc. (US) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017139778-A1 | THIENOPYRIDINE CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2017-08-17 | — | — | WO | disclosed |