Sugi Predict

Sugi Predict / Compounds / SCHEMBL19212264

SCHEMBL19212264

SCHEMBL19212264

CCOC(=O)c1c[c]ccc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.50
▸ ALDH1A1 P00352 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ CA12 O43570 4/20 0.42
▸ CA1 P00915 4/20 0.42
▸ CA2 P00918 4/20 0.42
▸ CA7 P43166 4/20 0.42
▸ CA9 Q16790 4/20 0.42
▸ CA14 Q9ULX7 4/20 0.42
▸ NPSR1 Q6W5P4 2/20 0.40
▸ TP53 P04637 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ JMJD6 Q6NYC1 1/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ HPGD P15428 2/20 0.40
▸ GLA P06280 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27897937 0.87 TSHR (0.50) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL129924 0.84 TSHR (0.60) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL971903 0.81 CA12 (0.56) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL1476818 0.81 KMT2A (0.41) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL27999935 0.80 TSHR (0.50) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL4738309 0.80 CYP4F2 (0.51) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL29258466 0.79 TSHR (0.53) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL1810786 0.79 TSHR (0.49) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL1809516 0.79 TSHR (0.49) TSHRALDH1A1HSD17B10CA12CA1
SCHEMBL7499134 0.79 TSHR (0.53) TSHRALDH1A1HSD17B10CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071506-B Substituted 2- (hetero) arylimidazolyl carboxamides as pest control agents 拜耳作物科学股份公司 2021-03-02 — — CN claimed
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-01-28 — — US claimed
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-14 — — US claimed
CN-109071506-A Substituted 2- (miscellaneous) Aryimidazole yl-carboxamides as pest control agent 拜耳作物科学股份公司 2018-12-21 — — CN claimed
EP-3414236-A1 SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2018-12-19 — — EP claimed
WO-2017137338-A1 SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-17 — — WO claimed
US-20220192185-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE BASF SE (DE) 2022-06-23 — — US disclosed
US-20220183278-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA BASF SE (DE) 2022-06-16 — — US disclosed
US-20220159957-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN BASF SE (DE) 2022-05-26 — — US disclosed
EP-3962269-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN BASF SE (DE) 2022-03-09 — — EP disclosed
CN-113795148-A Stabilization of suspension concentrates by highly sulfonated lignosulfonates 巴斯夫欧洲公司 2021-12-14 — — CN disclosed
CN-113795147-A Stabilization of suspension concentrates by ethoxylated glycerol triricinoleate 巴斯夫欧洲公司 2021-12-14 — — CN disclosed
CN-113784619-A Stabilization of suspension concentrates by hydrophobic fumed silica 巴斯夫欧洲公司 2021-12-10 — — CN disclosed
CN-104114555-A Pyrazolopyrimidine derivatives, process for their preparation and their therapeutic use SANOFI SA 2014-10-22 — — CN disclosed
CN-102348682-B 1,1,1-trifluoro-2-hydroxypropyl compounds HOFFMANN LA ROCHE 2014-07-30 — — CN disclosed
CN-102356068-B 2,3-diaryl- or heteroaryl-substituted 1,1,1-trifluoro-2-hydroxypropyl compounds HOFFMANN LA ROCHE 2014-04-23 — — CN disclosed
CN-101808992-B 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives HOFFMANN LA ROCHE 2012-09-26 — — CN disclosed
CN-102356068-A 2,3-diaryl- or heteroaryl-substituted 1,1,1-trifluoro-2-hydroxypropyl compounds HOFFMANN LA ROCHE 2012-02-15 — — CN disclosed
CN-102348682-A 1,1,1-trifluoro-2-hydroxypropyl compounds HOFFMANN LA ROCHE 2012-02-08 — — CN disclosed
CN-101808992-A 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives HOFFMANN LA ROCHE 2010-08-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190047982-A1 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 TSHR 1122/4885ALDH1A1 3432/4885HSD17B10 1818/4885
US-20220159957-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY ETHOXYLATED RICINOLEIN ERO1A, ERLIN2, ERLIN1 TSHR 3813/4885ALDH1A1 2619/4885HSD17B10 2583/4885
US-20220192185-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HIGHLY SULFONATED LIGNOSULFONATE LSS, STS, U2SURP TSHR 4730/4885ALDH1A1 571/4885HSD17B10 2720/4885
US-20220183278-A1 STABILIZATION OF SUSPENSION CONCENTRATES BY HYDROPHOBIC FUMED SILICA RCC1, SAMM50, PIGS TSHR 4520/4885ALDH1A1 2627/4885HSD17B10 3545/4885
US-10544124-B2 Substituted 2-(het)arylimidazolylcarboxyamides as pesticides DDT, CYP4X1, CYP4Z1 TSHR 1122/4885ALDH1A1 3432/4885HSD17B10 1818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.