SCHEMBL19214702

SCHEMBL19214702

Ic1nc2c(ccc3sc(I)nc32)s1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.35
LMNA P02545 4/20 0.35
MAPT P10636 4/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 4/20 0.33
HPGD P15428 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PRNP P04156 1/20 0.33
PKM P14618 1/20 0.31
MAPK1 P28482 1/20 0.31
PDPK1 O15530 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21395484 0.75 LMNA (0.61) GAALMNAMAPTMEN1KMT2A
SCHEMBL2750042 0.68 F2RL3 (0.46) GAALMNAMAPTMEN1KMT2A
SCHEMBL3908559 0.67 ALDH1A1 (0.54) GAALMNAMAPTMEN1KMT2A
SCHEMBL6118333 0.67 SMN1; SMN2 (0.59) GAALMNAMAPTMEN1KMT2A
SCHEMBL21412413 0.66 CA2 (0.53) GAALMNAMAPTMEN1KMT2A
SCHEMBL18863820 0.64 HSD17B10 (0.41) GAAALDH1A1
SCHEMBL17281505 0.63 NPC1 (0.44) GAALMNAMAPTMEN1KMT2A
SCHEMBL19001500 0.62 HRH3 (0.40) LMNAMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL1770192 0.61 NPC1 (0.46) GAALMNAMAPTMEN1KMT2A
SCHEMBL20710919 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11778893-B2 Indaceno derivatives as organic semiconductors CLAP CO., LTD. (KR) 2023-10-03 US disclosed
US-20210384434-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS CLAP CO., LTD. (KR) 2021-12-09 US disclosed
US-10388881-B2 Sorting of carbon nanotubes BASF SE (DE) 2019-08-20 US disclosed
US-10020456-B2 Ether-based polymers as photo-crosslinkable dielectrics BASF SE (DE) 2018-07-10 US disclosed
US-20170250358-A1 ETHER-BASED POLYMERS AS PHOTO-CROSSLINKABLE DIELECTRICS BASF SE (DE) 2017-08-31 US disclosed
US-20170229657-A1 SORTING OF CARBON NANOTUBES CLAP CO., LTD. (KR) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210384434-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS IPO11, CYP1B1, IDO1 GAA 3672/4885LMNA 2683/4885MAPT 2054/4885
US-11778893-B2 Indaceno derivatives as organic semiconductors IPO11, CYP1B1, IDO1 GAA 3672/4885LMNA 2683/4885MAPT 2054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.