SCHEMBL19001500

SCHEMBL19001500

Ic1nc2ncccc2s1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.40
CRBN Q96SW2 3/20 0.37
LTA4H P09960 3/20 0.37
DDB1 Q16531 1/20 0.35
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
TP53 P04637 2/20 0.35
TSHR P16473 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 2/20 0.34
HDAC8 Q9BY41 2/20 0.33
SCD O00767 1/20 0.33
NUDT1 P36639 1/20 0.33
GMNN O75496 1/20 0.33
HSP90AA1 P07900 1/20 0.33
MMP2 P08253 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29064014 0.78 KDM4E (0.46) HRH3CRBNLTA4HDDB1ALDH1A1
SCHEMBL21496679 0.77 HRH3 (0.41) HRH3CRBNLTA4HDDB1ALDH1A1
SCHEMBL30319909 0.75 PI4KA (0.46) HRH3CRBNLTA4HALDH1A1SMN1; SMN2
SCHEMBL1851678 0.75 PI4KA (0.46) HRH3CRBNLTA4HALDH1A1SMN1; SMN2
SCHEMBL29505248 0.75 HRH3 (0.40) HRH3CRBNLTA4HDDB1ALDH1A1
SCHEMBL780688 0.75 NR4A2 (0.42) HRH3CRBNLTA4HDDB1ALDH1A1
SCHEMBL1885424 0.75 HRH3 (0.40) HRH3CRBNLTA4HDDB1ALDH1A1
SCHEMBL4074962 0.75 HRH3 (0.40) HRH3CRBNLTA4HDDB1ALDH1A1
SCHEMBL23172529 0.74 RAB9A (0.40) HRH3LTA4HALDH1A1KDM4ETP53
Hydrochloric Acid SCHEMBL1891560 0.73 NR4A2 (0.41) HRH3CRBNLTA4HDDB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
US-11696491-B2 Organometallic compound, organic light-emitting device including the same and apparatus including the organometallic compound SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-20220190296-A1 LIGHT-EMITTING DEVICE AND AN ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-06-16 US disclosed
US-11158815-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-26 US disclosed
US-20210320154-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-14 US disclosed
US-11056664-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-06 US disclosed
US-20210167301-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AND APPARATUS INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-03 US disclosed
US-20200295279-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-09-17 US disclosed
US-10756274-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-25 US disclosed
US-20200099001-A1 ORGANIC LIGHT-EMITTING DEVICE, APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2020-03-26 US disclosed
US-10566545-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-18 US disclosed
US-10461263-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-10-29 US disclosed
US-20190027698-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-24 US disclosed
US-20190019964-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-17 US disclosed
US-20180158881-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20180097186-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-04-05 US disclosed
US-20180076396-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-15 US disclosed
US-20170294587-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 US disclosed
EP-3185328-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-06-28 EP disclosed
US-20170179401-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11158815-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 HRH3 2322/4885CRBN 1380/4885LTA4H 1141/4885
US-20180097186-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME C1S, C1R, C9 HRH3 2330/4885CRBN 892/4885LTA4H 1270/4885
US-10461263-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNA1, CCNE2 HRH3 1699/4885CRBN 595/4885LTA4H 1133/4885
US-20200099001-A1 ORGANIC LIGHT-EMITTING DEVICE, APPARATUS INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND LEF1, OCIAD1, OXA1L HRH3 4705/4885CRBN 3602/4885LTA4H 919/4885
US-11056664-B2 Organic light-emitting device EML4, L1CAM, OR10J3 HRH3 4708/4885CRBN 3365/4885LTA4H 562/4885
US-10566545-B2 Condensed cyclic compound and organic light-emitting device including the same C1S, C1R, C9 HRH3 2330/4885CRBN 892/4885LTA4H 1270/4885
US-20190019964-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME LEF1, OCIAD1, POU2F1 HRH3 4715/4885CRBN 3502/4885LTA4H 3208/4885
US-20180076396-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNA1, CCNE2 HRH3 1699/4885CRBN 595/4885LTA4H 1133/4885
US-20200295279-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE ORC3, ZC3HAV1L, ICMT HRH3 3785/4885CRBN 2061/4885LTA4H 1040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.