Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 known ✓ | P25103 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921591 | 0.82 | HTR2A (0.38) | HTR6HTR2ASIGMAR1TACR1 | |
| Hydrochloric Acid SCHEMBL4479517 | 0.81 | HTR2A (0.35) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL9860034 | 0.80 | HTR2A (0.37) | HTR6HTR2ASIGMAR1TACR1 | |
| SCHEMBL6673086 | 0.76 | HTR2A (0.36) | HTR6HTR2ASIGMAR1TACR1 | |
| Hydrochloric Acid SCHEMBL4476293 | 0.75 | HTR6 (0.43) | HTR6HTR2ASIGMAR1TACR1 | |
| Hydrochloric Acid SCHEMBL30216613 | 0.75 | HTR2A (0.36) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL8676551 | 0.74 | KDM4E (0.33) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL5034593 | 0.74 | SIGMAR1 (0.38) | HTR6HTR2ASIGMAR1TACR1 | |
| SCHEMBL30084485 | 0.74 | SIGMAR1 (0.38) | HTR6HTR2ASIGMAR1TACR1 | |
| Hydrochloric Acid SCHEMBL8853905 | 0.73 | HTR2A (0.34) | HTR6HTR2ASIGMAR1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1671983-B1 | Catalysts compositions for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA SA (ES) | 2009-02-25 | — | — | EP | claimed |