SCHEMBL19218372

SCHEMBL19218372

c1ccc2c(c1)-c1ccccc1C21c2ccccc2-c2cccc(N(c3ccc(-c4ccc5c(c4)oc4ccccc45)cc3)c3ccc4c5ccccc5c5ccccc5c4c3)c21

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.33
MMP13 P45452 1/20 0.33
AHR P35869 1/20 0.32
ALOX5 P09917 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
HCRTR1 O43613 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31
PRKDC P78527 1/20 0.31
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19218389 1.00 MMP12 (0.33) MMP12MMP13AHRALOX5KDM4E
SCHEMBL19218391 0.98 PLA2G2A (0.33) MMP12MMP13AHRALOX5KDM4E
SCHEMBL19218388 0.95 HSP90AA1 (0.32) ALOX5KDM4EMEN1ALDH1A1MAPT
SCHEMBL19218382 0.95 HSP90AA1 (0.32) ALOX5KDM4EMEN1ALDH1A1MAPT
SCHEMBL19218373 0.95 HCRTR1 (0.33) MMP12MMP13AHRALOX5KDM4E
SCHEMBL19218395 0.93 PLA2G2A (0.33) ALOX5KDM4EMEN1ALDH1A1MAPT
SCHEMBL25496520 0.93 MMP12 (0.33) MMP12MMP13AHRALOX5KDM4E
SCHEMBL19218375 0.92 AHR (0.35) AHRALOX5KDM4EMEN1ALDH1A1
SCHEMBL19218386 0.92 ALOX5 (0.34) AHRALOX5KDM4EMEN1ALDH1A1
SCHEMBL15213665 0.91 AHR (0.33) MMP12MMP13AHRALOX5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10243148-B2 Aromatic amine compound, and organic electroluminescent elements including the compound IDEMITSU KOSAN CO., LTD. (JP) 2019-03-26 US disclosed
US-20170229649-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed
US-20170229649-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10243148-B2 Aromatic amine compound, and organic electroluminescent elements including the compound H1-10, H1-0, H1-4 MMP12 4744/4885MMP13 4833/4885AHR 60/4885
US-20170229649-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, LEF1, PIEZO1 MMP12 4233/4885MMP13 4785/4885AHR 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.