Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2220771 | 1.00 | THRB (0.59) | THRBMEN1KMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL29205026 | 1.00 | THRB (0.59) | THRBMEN1KMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL1355955 | 1.00 | THRB (0.59) | THRBMEN1KMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL6929104 | 1.00 | THRB (0.59) | THRBMEN1KMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL17599238 | 1.00 | THRB (0.59) | THRBMEN1KMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL293987 | 1.00 | THRB (0.59) | THRBMEN1KMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL17141305 | 1.00 | THRB (0.59) | THRBMEN1KMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL293988 | 1.00 | THRB (0.59) | THRBMEN1KMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL181242 | 1.00 | THRB (0.59) | THRBMEN1KMT2AFFAR3LCK | |
| Acetic Acid SCHEMBL2905730 | 0.97 | THRB (0.56) | THRBMEN1KMT2AFFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151942-A1 | DEVICE FOR CONVERTING THERMAL ENERGY OF AN EXTERNAL HEAT SOURCE INTO ELECTRICAL ENERGY | HAESE FRANK (DE) | 2023-08-17 | — | — | WO | disclosed |
| EP-4227604-A1 | DEVICE FOR CONVERTING THERMAL ENERGY OF AN EXTERNAL HEAT SOURCE INTO ELECTRICAL ENERGY | Haese, Frank (DE) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022108919-A1 | PROBES, SYSTEMS, AND METHODS FOR MAGNETIC RESONANCE PH SENSING | THE GENERAL HOSPITAL CORPORATION (US) | 2022-05-27 | — | — | WO | disclosed |
| US-8263548-B2 | Metal-binding compounds and uses therefor | DMI BIOSCIENCES, INC. | 2012-09-11 | — | — | US | disclosed |
| US-8188215-B2 | Metal-binding compounds and uses therefor | AMPIO PHARMACEUTICALS, INC. | 2012-05-29 | — | — | US | disclosed |
| US-20110263817-A1 | METAL-BINDING COMPOUNDS AND USES THEREFOR | AMPIO PHARMACEUTICALS, INC. | 2011-10-27 | — | — | US | disclosed |
| US-8017728-B2 | Metal-binding compounds and uses therefor | AMPIO PHARMACEUTICALS, INC. | 2011-09-13 | — | — | US | disclosed |
| US-20110212902-A1 | METAL-BINDING COMPOUNDS AND USES THEREFOR | AMPIO PHARMACEUTICALS, INC. | 2011-09-01 | — | — | US | disclosed |
| US-20110212903-A1 | METAL-BINDING COMPOUNDS AND USES THEREFOR | AMPIO PHARMACEUTICALS, INC. | 2011-09-01 | — | — | US | disclosed |
| US-7973008-B2 | Metal-binding compounds and uses therefor | DMI BIOSCIENCES, INC. | 2011-07-05 | — | — | US | disclosed |
| US-7592304-B2 | Metal-binding compounds and uses therefor | DMI LIFE SCIENCES, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| US-20050215468-A1 | Metal-binding compounds and uses therefor | AMPIO PHARMACEUTICALS, INC. | 2005-09-29 | — | — | US | disclosed |
| US-20030158111-A1 | Methods and products for oral care | AMPIO PHARMACEUTICALS, INC. | 2003-08-21 | — | — | US | disclosed |
| US-20030130185-A1 | Metal-binding compounds and uses therefor | AMPIO PHARMACEUTICALS, INC. | 2003-07-10 | — | — | US | disclosed |
| US-20030060408-A1 | Metal-binding compounds and uses therefor | AMPIO PHARMACEUTICALS, INC. | 2003-03-27 | — | — | US | disclosed |
| US-4563288-A | N-Alkyl isostearamide antistatic agents, detergent compositions containing such agents, and processes for washing laundry in the presence of such agents, and with such compositions | COLGATE-PALMOLIVE COMPANY (US) | 1986-01-07 | — | — | US | disclosed |
| US-4497715-A | N-Alkylisostearamides as antistatic agents | COLGATE-PALMOLIVE COMPANY (US) | 1985-02-05 | — | — | US | disclosed |
| US-4283192-A | DETERGENTS | COLGATE-PALMOLIVE COMPANY (US) | 1981-08-11 | — | — | US | disclosed |
| US-4272413-A | Dialkylurea textile softening and antistatic agents | COLGATE-PALMOLIVE COMPANY | 1981-06-09 | — | — | US | disclosed |
| US-4260497-A | DETERGENTS | COLGATE-PALMOLIVE COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130185-A1 | Metal-binding compounds and uses therefor | SLC39A11, ROS1, NOX4 | THRB 3100/4885MEN1 3012/4885KMT2A 3925/4885 |
| US-20030060408-A1 | Metal-binding compounds and uses therefor | SLC39A11, ROS1, NOX4 | THRB 3100/4885MEN1 3012/4885KMT2A 3925/4885 |
| US-20030158111-A1 | Methods and products for oral care | MPO, IL1B, SOD1 | THRB 2042/4885MEN1 4291/4885KMT2A 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.