SCHEMBL1922945

SCHEMBL1922945

O=Cc1cc(F)c(O)c(F)c1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.52
XDH P47989 1/20 0.45
KDM4E B2RXH2 1/20 0.41
PTGS2 P35354 1/20 0.41
RAB9A P51151 1/20 0.41
ALDH5A1 P51649 1/20 0.40
ABAT P80404 1/20 0.40
ALOX5 P09917 1/20 0.39
NFKB1 P19838 1/20 0.39
STAT3 P40763 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
NFE2L2 Q16236 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30822600 0.90 XDH (0.52) ERN1XDHKDM4EPTGS2RAB9A
SCHEMBL1056033 0.90 XDH (0.52) ERN1XDHKDM4EPTGS2RAB9A
SCHEMBL29955970 0.86 ERN1 (0.67) ERN1
SCHEMBL1299499 0.84 MCL1 (0.46) ERN1XDHALDH1A1
SCHEMBL29954909 0.84 MCL1 (0.46) ERN1XDHALDH1A1
SCHEMBL24981909 0.84 ERN1 (0.44) ERN1XDHKDM4EPTGS2RAB9A
SCHEMBL12593986 0.84 PTGS1 (0.47) ERN1XDHPTGS2ALOX5
SCHEMBL987816 0.84 ERN1 (0.44) ERN1XDH
SCHEMBL31063495 0.84 ERN1 (0.44) ERN1XDH
SCHEMBL21358410 0.83 KDM4E (0.44) ERN1XDHKDM4EALOX5NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081885-A Substituted phenyl glycoside compound and preparation method and application thereof 浙江大学 2025-06-03 CN claimed
CN-119912821-A Flame-retardant high-temperature-resistant composite epoxy resin material and preparation method thereof 铜陵善纬新材料科技有限公司 2025-05-02 CN claimed
CN-118619850-B Fluorescent probe for screening monoamine oxidase A inhibitor and preparation method and application thereof 山东省中医药研究院 2024-10-15 CN claimed
CN-118619850-A Fluorescent probe for screening monoamine oxidase A inhibitor and preparation method and application thereof 山东省中医药研究院 2024-09-10 CN claimed
CN-110423487-B Rhodol derivative dye and application thereof 湖南大学 2021-01-22 CN claimed
JP-4587669-B2 2010-11-24 JP claimed
JP-2005509662-A 2005-04-14 JP claimed
EP-1443915-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES Cutanix Corporation (US) 2004-08-11 EP claimed
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP claimed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US claimed
WO-2003043621-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES CUTANIX CORPORATION (US) 2003-05-30 WO claimed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO claimed
US-12625141-B2 Fluorescent dye, preparation method and uses thereof FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD (CN) 2026-05-12 US disclosed
US-20250270162-A1 KETONE INHIBITORS OF LYSINE GINGIPAIN LIGHTHOUSE PHARMACEUTICALS, INC. (US) 2025-08-28 US disclosed
US-20250188044-A1 TRIAZOLONE COMPOUND, PHARMACEUTICAL USE THEREOF AND PHARMACEUTICAL COMPOSITION HARBIN MEDISAN PHARMACEUTICAL CO., LTD. (CN) 2025-06-12 US disclosed
CN-120081885-A Substituted phenyl glycoside compound and preparation method and application thereof 浙江大学 2025-06-03 CN disclosed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO disclosed
EP-0325245-B1 Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use TANABE SEIYAKU CO (JP) 1993-10-20 EP disclosed
US-4948810-A PLATELET AGGREGATION INHIBITORS TANABE SEIYAKU CO., LTD. (JP) 1990-08-14 US disclosed
EP-0325245-A1 Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use TANABE SEIYAKU CO., LTD. (JP) 1989-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments TYR, HRH1, HRH2 ERN1 4830/4885XDH 175/4885KDM4E 2158/4885
US-20250188044-A1 TRIAZOLONE COMPOUND, PHARMACEUTICAL USE THEREOF AND PHARMACEUTICAL COMPOSITION PPARD, PPARA, PPARG ERN1 3962/4885XDH 1092/4885KDM4E 4377/4885
US-12625141-B2 Fluorescent dye, preparation method and uses thereof AMY1A, AMY2A, SUB1 ERN1 127/4885XDH 626/4885KDM4E 4262/4885
US-20250270162-A1 KETONE INHIBITORS OF LYSINE GINGIPAIN PHYKPL, ENPEP, PREP ERN1 2625/4885XDH 3265/4885KDM4E 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.