Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230249 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP1A2POLBCYP2C9CHRM2 | |
| SCHEMBL19209540 | 0.80 | CHRM2 (0.48) | CHRM2CHRM4CHRM1CHRM3GAA | |
| SCHEMBL3712707 | 0.80 | MEN1 (0.59) | POLBCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7971782 | 0.77 | SIGMAR1 (0.69) | SIGMAR1ACKR3 | |
| SCHEMBL2862442 | 0.77 | ALDH1A1 (0.60) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL29132198 | 0.76 | MEN1 (0.58) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL19230247 | 0.76 | USP2 (0.41) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL19230082 | 0.76 | USP2 (0.41) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7986044 | 0.75 | SIGMAR1 (0.55) | POLBCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL104620 | 0.75 | USP2 (0.47) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136769-A1 | PEPTIDE DRUG CONJUGATES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-10 | — | — | WO | disclosed |