Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712707 | 0.95 | MEN1 (0.59) | SIGMAR1MEN1KMT2AKCNH2POLB | |
| SCHEMBL7989733 | 0.93 | SIGMAR1 (0.64) | SIGMAR1CHRM3ACKR3 | |
| SCHEMBL8210703 | 0.87 | KMT2A (0.55) | MEN1KMT2ACHRM3CHRM2CHRM4 | |
| SCHEMBL7971782 | 0.87 | SIGMAR1 (0.69) | SIGMAR1ACKR3 | |
| SCHEMBL8526553 | 0.86 | SIGMAR1 (0.59) | SIGMAR1KMT2ACHRM3 | |
| SCHEMBL7971893 | 0.85 | MEN1 (0.52) | SIGMAR1ACHEMEN1KMT2AKCNH2 | |
| SCHEMBL9054221 | 0.85 | L3MBTL1 (0.64) | SIGMAR1ACHEMEN1KMT2AKCNH2 | |
| SCHEMBL27648293 | 0.83 | MAPT (0.56) | SIGMAR1ACHEMEN1KMT2AKCNH2 | |
| SCHEMBL2850833 | 0.83 | KDM1A (0.48) | SIGMAR1MEN1KMT2AKCNH2POLB | |
| SCHEMBL7971891 | 0.83 | SIGMAR1 (0.80) | SIGMAR1ACHEMEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |