Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712707 | 0.81 | MEN1 (0.59) | CHRM2CHRM4CHRM1CHRM3GAA | |
| SCHEMBL19230233 | 0.80 | ALDH1A1 (0.50) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL19230249 | 0.80 | ALDH1A1 (0.50) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL7971782 | 0.79 | SIGMAR1 (0.69) | ACKR3SIGMAR1 | |
| SCHEMBL2862442 | 0.79 | ALDH1A1 (0.60) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL29132198 | 0.78 | MEN1 (0.58) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL7986044 | 0.77 | SIGMAR1 (0.55) | CHRM2CHRM4CHRM1CHRM3GAA | |
| SCHEMBL26960504 | 0.76 | MEN1 (0.51) | CHRM2CHRM4CHRM1CHRM3STS | |
| SCHEMBL10261934 | 0.76 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3STS | |
| SCHEMBL4720508 | 0.76 | HSD11B1 (0.60) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136769-A1 | PEPTIDE DRUG CONJUGATES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017136769-A1 | PEPTIDE DRUG CONJUGATES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-10 | — | — | WO | disclosed |