Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230651 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL3025176 | 0.80 | MAPT (0.68) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL11278452 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL27927947 | 0.72 | ALDH1A1 (0.76) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL19230796 | 0.70 | DRD2 (0.42) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL2530426 | 0.70 | ALDH1A1 (0.72) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL2530427 | 0.70 | ALDH1A1 (0.72) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL19230794 | 0.70 | MAPT (0.42) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL30109399 | 0.69 | MEN1 (0.63) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL11283392 | 0.69 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-A | FXR receptor stimulating agents | 山东轩竹医药科技有限公司 | 2018-09-28 | — | — | CN | disclosed |