Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230697 | 0.81 | KDM4E (0.51) | L3MBTL1ALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL22871232 | 0.80 | HPGD (0.39) | HTTALDH1A1MAPTMAPK1MAOA | |
| SCHEMBL19230819 | 0.80 | GRM5 (0.42) | PKMGRM5HTTALDH1A1MAPT | |
| SCHEMBL19008193 | 0.80 | PKM (0.45) | PKMGRM5HTTLMNAL3MBTL1 | |
| SCHEMBL19230698 | 0.79 | GRM5 (0.40) | PKMGRM5LMNA | |
| SCHEMBL19007909 | 0.79 | L3MBTL1 (0.51) | PKMGRM5HTTLMNAL3MBTL1 | |
| SCHEMBL19230555 | 0.78 | GRM5 (0.42) | PKMGRM5L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL24461271 | 0.76 | PKM (0.45) | PKMGRM5HTTLMNAL3MBTL1 | |
| SCHEMBL19273376 | 0.76 | NUDT1 (0.49) | PKML3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL24497447 | 0.76 | PKM (0.45) | PKMGRM5HTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |